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Found 4 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM496928'
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM496928(GC376 | cmdc.202100576, 14c)
Affinity DataIC50:  30nMAssay Description:Inhibition of His/SUMO tagged SARS-CoV2 main protease expressed in Escherichia coli BL21 (DE3) cells using Dabcyl-KTSAVLQSGFRKME-Edans as substrate p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM496928(GC376 | cmdc.202100576, 14c)
Affinity DataIC50:  330nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Experimental Drug Development Centre

LigandPNGBDBM496928(GC376 | cmdc.202100576, 14c)
Affinity DataIC50:  4.40E+3nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM496928(GC376 | cmdc.202100576, 14c)
Affinity DataEC50: >2.00E+3nMAssay Description:Inhibition of eGFP fused SARS-CoV2 main protease transfected in HEK293T/17 cells incubated for 72 hrs by fluorescence based flow cytometry analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed