Found 5 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM25628'
Affinity DataIC50: 0.130nMpH: 7.2 T: 2°CAssay Description:Activity of human recombinant B-Raf protein was assessed in vitro by assay of the incorporation of radiolabeled phosphate to recombinant MAP kinase (...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of b-Raf in human A375 cells assessed phosphorylation of ERKMore data for this Ligand-Target Pair
Affinity DataKd: 0.180nMAssay Description:Binding constant for BRAF(V600E) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.190nMAssay Description:Binding constant for BRAF kinase domainMore data for this Ligand-Target Pair