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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50328616'
TargetSerine/threonine-protein kinase mTOR(Mus musculus (Mouse))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50328616(1-(4-(4-Acetylpiperazin-1-yl)-3-(trifluoromethyl)p...)
Affinity DataIC50:  3nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50328616(1-(4-(4-Acetylpiperazin-1-yl)-3-(trifluoromethyl)p...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed