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Found 4 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50262685'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDR by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataIC50:  25.1nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataIC50:  25.1nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human KDR in presence of (33P)gamma ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed