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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-gated L-type calcium channel' and Ligand = 'BDBM50000374'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated L-type calcium channel


(Homo sapiens (Human))
BDBM50000374
PNG
(Acetic acid 7-bromo-1-(2-dimethylamino-ethyl)-6-me...)
Show SMILES COc1ccc(cc1)[C@@H]1Cc2c(OC)c(Br)ccc2N(CCN(C)C)C(=O)[C@@H]1OC(C)=O
Show InChI InChI=1S/C24H29BrN2O5/c1-15(28)32-23-18(16-6-8-17(30-4)9-7-16)14-19-21(11-10-20(25)22(19)31-5)27(24(23)29)13-12-26(2)3/h6-11,18,23H,12-14H2,1-5H3/t18-,23+/m0/s1
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/an/a 120n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro ability to displace the specific binding of [3H]-diltiazem to diltiazem receptor in guinea pig skeletal muscle.


J Med Chem 35: 780-93 (1992)


Article DOI: 10.1021/jm00082a020
BindingDB Entry DOI: 10.7270/Q2K64H14
More data for this
Ligand-Target Pair