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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50257441'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50257441
PNG
(CHEMBL493145 | ethyl 2-(4-(4-(2-(dimethylamino)eth...)
Show SMILES CCOC(=O)c1sc(Nc2nc(cc(n2)N2CCN(CCN(C)C)CC2)N2CCN(C)CC2)nc1C
Show InChI InChI=1S/C24H39N9O2S/c1-6-35-22(34)21-18(2)25-24(36-21)28-23-26-19(32-13-8-30(5)9-14-32)17-20(27-23)33-15-11-31(12-16-33)10-7-29(3)4/h17H,6-16H2,1-5H3,(H,25,26,27,28)
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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of PDE5


Bioorg Med Chem Lett 19: 1935-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.060
BindingDB Entry DOI: 10.7270/Q2TM7B02
More data for this
Ligand-Target Pair