Affinity DataIC50: 720nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate pretreated 60 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat brain MAO-B using 14C-phenylethylamine as substrate preincubated for 60 mins followed by substrate addition and measured after 20 m...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MAOBMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine as substrate preincubated for 60 mins followed by substrate addition by ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine as substrate preincubated for 60 mins followed by substrate addition by ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.06E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine as substrate preincubated for 60 mins followed by substrate addition by ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rat brain MAO-A using 14C-5-hydroxytryptamine creatinine disulfate as substrate preincubated for 60 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MAOAMore data for this Ligand-Target Pair