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Found 9 of ic50 for monomerid = 12581
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human FPPS expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against the human recombinant FPPSase(Farnesyl diphosphate) enzymeMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Affinity DataIC50:  353nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Affinity DataIC50:  500nMAssay Description:Cardioselectivity for the beta-1 adrenergic receptor was determined against isoprenaline (antagonism) in isolated guinea pig tracheaMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME? (M)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Wroclaw University Of Technology

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibitory activity against the human recombinant geranylgeranyl diphosphate synthase (GGPPSase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Affinity DataIC50:  1.82E+5nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed