TargetAlpha-1-antitrypsin-related protein(Homo sapiens)
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Binding affinity to ATR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant full length ATR using GST-cMyc-p53 as substrate incubated for 40 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant FLAG-tagged full length ATR expressed in mammalian cell line co-expressing human recombinant cMyc-tagged full length ...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of ATR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Estimated IC50 values are as follows (obtained using STANDARD KINASEPROFILER).More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)
Curated by ChEMBL
Vertex Pharmaceuticals (Europe)
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair