Affinity DataIC50: 1.5nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in HEK293 cell membranes assessed as suppression of [35S]GTPgammaS binding incubated for 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in HEK293 cell membranes assessed as suppression of [35S]GTPgammaS binding incubated for 60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Allosteric antagonist activity at human CB1 receptor expressed in CHO-RD-HGA16 cells overexpressing Galpha16 assessed as inhibition of CP55940-stimul...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Allosteric modulation of human CB1 receptor expressed in CHO cells co-expressing Galpha16 assessed as inhibition of CP55,940-induced calcium mobiliza...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Allosteric antagonist activity at human CB1 receptor by Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Allosteric modulator activity at human CB1 receptor expressed in CHO-RD-HGA16 cells co-expressing Galpha16 assessed as suppression of 100 nM CP55,940...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human CB2 receptor stably expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization afte...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Allosteric antagonist activity at human CB1 receptor by Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Allosteric modulation of CB1 receptor (unknown origin) assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Allosteric modulator activity at human CB1 receptor expressed in CHO-RD-HGA16 cells co-expressing Galpha16 assessed as suppression of 100 nM CP55,940...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Allosteric modulation of CB1 receptor in rat cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Allosteric modulation of CB1 receptor in HEK293 cell membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Allosteric antagonist activity at human CB1 receptor expressed in HEK293 cell membrane assessed as inhibition of CP55940-stimulated [35S]GTPgammaS bi...More data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Allosteric modulation of CB1 receptor (unknown origin) assessed as inhibition of CP55940-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Allosteric antagonist activity at mouse CB1 receptor by GTPgammaS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Allosteric antagonist activity at mouse CB1 receptor by GTPgammaS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Allosteric modulator activity at CB1 receptor in mouse cerebellar membranes assessed as suppression of 1 uM CP55,940-induced [35S]GTPgammaS binding i...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Allosteric modulator activity at CB1 receptor in mouse cerebellar membranes assessed as suppression of 1 uM CP55,940-induced [35S]GTPgammaS binding i...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Allosteric modulator activity at CB1 receptor in mouse cerebellar membranes assessed as suppression of 1 uM CP55,940-induced [35S]GTPgammaS binding i...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Allosteric modulator activity at CB1 receptor in mouse cerebellar membranes assessed as suppression of 1 uM CP55,940-induced [35S]GTPgammaS binding i...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Negative allosteric modulation of human CB1 receptor expressed in HEK293 cells assessed as inhibition of 33 nM CP55,940-induced SRE transcriptional a...More data for this Ligand-Target Pair
Affinity DataIC50: 288nMAssay Description:Allosteric modulator activity at CB1 receptor in mouse cerebellar membranes assessed as suppression of 100 nM CP55,940-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataIC50: 288nMAssay Description:Allosteric modulator activity at CB1 receptor in mouse cerebellar membranes assessed as suppression of 100 nM CP55,940-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataIC50: 288nMAssay Description:Allosteric modulator activity at CB1 receptor in mouse cerebellar membranes assessed as suppression of 100 nM CP55,940-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataIC50: 288nMAssay Description:Allosteric modulator activity at CB1 receptor in mouse cerebellar membranes assessed as suppression of 100 nM CP55,940-induced [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Allosteric antagonist activity at N-terminal 3HA-tagged human CB1 receptor expressed in HEK293 cells assessed as reduction in CP55940-stimulated inhi...More data for this Ligand-Target Pair
Affinity DataIC50: 455nMAssay Description:Allosteric modulator activity at human CB1 receptor expressed in HEK293 cell membranes assessed as suppression of 100 nM CP55,940-induced [35S]GTPgam...More data for this Ligand-Target Pair
Affinity DataIC50: 455nMAssay Description:Allosteric modulator activity at human CB1 receptor expressed in HEK293 cell membranes assessed as suppression of 100 nM CP55,940-induced [35S]GTPgam...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of FAAH in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+3nMAssay Description:Allosteric modulator activity at human CB1 receptor expressed in HEK293 cells assessed as suppression of 100 nM CP55,940-induced reduction in forskol...More data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+3nMAssay Description:Allosteric modulator activity at human CB1 receptor expressed in HEK293 cells assessed as suppression of 100 nM CP55,940-induced reduction in forskol...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Antagonist activity at human CB2 receptor expressed in CHO-RD-HGA16 cells overexpressing Galpha16 assessed as inhibition of CP55940-stimulated calciu...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human CB2 receptor expressed in CHO cells co-expressing Galpha16 assessed as inhibition of EC80 CP55,940-induced calcium mobil...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human CB2 receptor expressed in CHO cells co-expressing Galpha16 assessed as inhibition of CP55,940-induced calcium mobilizati...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from human CB1 receptor expressed in HEK293 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human CB2 receptor expressed in CHO cells co-expressing Galpha16 assessed as inhibition of EC80 CP55,940-induced calcium mobil...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAGL in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair