Compile Data Set for Download or QSAR
maximum 50k data
Found 39 of ic50 for monomerid = 50279080
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr)4:1 as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using poly (Glu, Tyr)4:1 as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human VEGFR2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  13nMAssay Description:Inhibition of mouse GST-fused VEGFR2 expressed in Sf9 insect cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human GST-fused VEGFR2 expressed in Sf9 insect cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human FGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  104nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  108nMAssay Description:Inhibition of human FGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  156nMAssay Description:Inhibition of human SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  156nMAssay Description:Inhibition of human SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  195nMAssay Description:Inhibition of human LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  195nMAssay Description:Inhibition of human LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50:  610nMAssay Description:Inhibition of human FGFR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Plk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human InsRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human IGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Boehringer Ingelheim Austria

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279080((Z)-3-[(4-{Methyl-[2-(4-methylpiperazin-1-yl)acety...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed