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Compile Data Set for Download or QSAR

Found 5 hits of kd for UniProtKB: P19020   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50038276
PNG
((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Show SMILES CCCN(C\C=C\I)C1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H22INO/c1-2-9-18(10-3-8-17)15-6-4-13-5-7-16(19)12-14(13)11-15/h3,5,7-8,12,15,19H,2,4,6,9-11H2,1H3/b8-3+
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GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 0.480n/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Binding affinity was tested against dopamine receptor D3 in rat striatal membarane homogenate


J Med Chem 36: 4308-12 (1994)


Article DOI: 10.1021/jm00078a021
BindingDB Entry DOI: 10.7270/Q2TB15ZH
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50020222
PNG
((+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthal...)
Show SMILES CCCN(CCC)C1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3
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CHEMBL
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PC sid
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Article
PubMed
n/an/an/a 0.670n/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Tested for binding affinity against dopamine receptor D3


J Med Chem 36: 4308-12 (1994)


Article DOI: 10.1021/jm00078a021
BindingDB Entry DOI: 10.7270/Q2TB15ZH
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50007692
PNG
(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12
Show InChI InChI=1S/C24H32N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23/h1-2,7-8H,3-6,9-18H2
MMDB

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Article
PubMed
n/an/an/a 334n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for its effect on dopamine saturation analysis


J Med Chem 29: 359-69 (1986)


Article DOI: 10.1021/jm00153a010
BindingDB Entry DOI: 10.7270/Q24X58C9
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50038276
PNG
((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Show SMILES CCCN(C\C=C\I)C1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H22INO/c1-2-9-18(10-3-8-17)15-6-4-13-5-7-16(19)12-14(13)11-15/h3,5,7-8,12,15,19H,2,4,6,9-11H2,1H3/b8-3+
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 0.130n/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Binding affinity was tested against dopamine receptor D3 in the absence of NaCl


J Med Chem 36: 4308-12 (1994)


Article DOI: 10.1021/jm00078a021
BindingDB Entry DOI: 10.7270/Q2TB15ZH
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (Rat))
BDBM50043603
PNG
(7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro...)
Show SMILES CCCN(C\C=C\I)[C@@H]1CCc2ccc(O)cc2C1
Show InChI InChI=1S/C16H22INO/c1-2-9-18(10-3-8-17)15-6-4-13-5-7-16(19)12-14(13)11-15/h3,5,7-8,12,15,19H,2,4,6,9-11H2,1H3/b8-3+/t15-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 0.0500n/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Binding affinity was tested against dopamine receptor D3 in Sf9 cells


J Med Chem 36: 4308-12 (1994)


Article DOI: 10.1021/jm00078a021
BindingDB Entry DOI: 10.7270/Q2TB15ZH
More data for this
Ligand-Target Pair