TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 21nM ΔG°: -10.9kcal/mole IC50: 45nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 130nM ΔG°: -9.77kcal/mole IC50: 270nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 130nM ΔG°: -9.77kcal/mole IC50: 420nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 130nM ΔG°: -9.77kcal/mole IC50: 430nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 160nM ΔG°: -9.64kcal/mole IC50: 340nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 160nM ΔG°: -9.64kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 169nM ΔG°: -9.60kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 170nM ΔG°: -9.60kcal/mole IC50: 540nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 191nM ΔG°: -9.53kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 196nM ΔG°: -9.51kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 197nM ΔG°: -9.51kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 240nM ΔG°: -9.39kcal/mole IC50: 780nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 251nM ΔG°: -9.36kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 282nM ΔG°: -9.29kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 290nM ΔG°: -9.27kcal/mole IC50: 830nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 320nM ΔG°: -9.21kcal/mole IC50: 710nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 320nM ΔG°: -9.21kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 327nM ΔG°: -9.20kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 352nM ΔG°: -9.15kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 355nM ΔG°: -9.15kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 379nM ΔG°: -9.11kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 380nM ΔG°: -9.10kcal/mole IC50: 970nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 380nM ΔG°: -9.10kcal/mole IC50: 1.10E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 418nM ΔG°: -9.05kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 427nM ΔG°: -9.03kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 443nM ΔG°: -9.01kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 450nM ΔG°: -9.00kcal/mole IC50: 1.40E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 450nM ΔG°: -9.00kcal/mole IC50: 1.40E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 453nM ΔG°: -9.00kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 472nM ΔG°: -8.97kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 519nM ΔG°: -8.91kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 530nM ΔG°: -8.90kcal/mole IC50: 1.40E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 560nM ΔG°: -8.87kcal/mole IC50: 1.50E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 560nM ΔG°: -8.87kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 590nM ΔG°: -8.83kcal/mole IC50: 1.30E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 590nM ΔG°: -8.83kcal/mole IC50: 1.90E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 590nM ΔG°: -8.83kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 605nM ΔG°: -8.82kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 655nM ΔG°: -8.77kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 662nM ΔG°: -8.76kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 678nM ΔG°: -8.75kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 701nM ΔG°: -8.73kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 707nM ΔG°: -8.72kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 713nM ΔG°: -8.72kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 714nM ΔG°: -8.72kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 755nM ΔG°: -8.68kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 771nM ΔG°: -8.67kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 780nM ΔG°: -8.66kcal/mole IC50: 1.70E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 816nM ΔG°: -8.63kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 844nM ΔG°: -8.61kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair