Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50017329
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601257(CHEMBL5178276)
Affinity DataIC50:  48nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601254(CHEMBL5190048)
Affinity DataIC50:  61nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601255(CHEMBL5172911)
Affinity DataIC50:  69nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601258(CHEMBL5198248)
Affinity DataIC50:  93nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50:  260nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601256(CHEMBL5193934)
Affinity DataIC50:  440nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601253(CHEMBL5172081)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50601252(CHEMBL5171569)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of MTase activity of SARS-CoV-2 NSP14 expressed in Escherichia coli BL21(DE3) using GpppA and SAM as substrate preincubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed