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Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50017627
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM496902(CVD-0018409 | PF-07321332 | US11351149, Example 13...)
Affinity DataIC50:  54nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 fluorogenic peptide as substrate incubated for 30 mins and measured by FRET...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603510(CHEMBL5205985)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 fluorogenic peptide as substrate incubated for 30 mins and measured by FRET...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603508(CHEMBL5184053)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 fluorogenic peptide as substrate incubated for 30 mins and measured by FRET...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603509(CHEMBL1479456)
Affinity DataIC50:  3.61E+4nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 fluorogenic peptide as substrate incubated for 30 mins and measured by FRET...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed