Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with all data for entry = 50043074
TargetHistone deacetylase 3(Homo sapiens (Human))
Congenia s.r.l.

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
Affinity DataIC50: 55nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Congenia s.r.l.

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccccc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C23H24N2O4/c26-20-15-23(10-12-25(13-11-23)16-18-4-2-1-3-5-18)29-21-8-6-17(14-19(20)21)7-9-22(27)24-28/h1-9,14,28H,10-13,15-16H2,(H,24,27)
Affinity DataIC50: 65nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Congenia s.r.l.

Curated by ChEMBL
LigandPNGBDBM50435605(CHEMBL2390999)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCN(Cc4ccccc4)CC3)NC(=O)c2c1
Show InChI InChI=1S/C22H23N3O4/c26-20(24-28)9-7-16-6-8-19-18(14-16)21(27)23-22(29-19)10-12-25(13-11-22)15-17-4-2-1-3-5-17/h1-9,14,28H,10-13,15H2,(H,23,27)(H,24,26)/b9-7+
Affinity DataIC50: 87nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Congenia s.r.l.

Curated by ChEMBL
LigandPNGBDBM50435604(CHEMBL2390995)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccc(F)cc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C23H23FN2O4/c24-18-5-1-17(2-6-18)15-26-11-9-23(10-12-26)14-20(27)19-13-16(3-7-21(19)30-23)4-8-22(28)25-29/h1-8,13,29H,9-12,14-15H2,(H,25,28)
Affinity DataIC50: 90nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Congenia s.r.l.

Curated by ChEMBL
LigandPNGBDBM50435606(CHEMBL2390996)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(CCc4ccccc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C24H26N2O4/c27-21-17-24(11-14-26(15-12-24)13-10-18-4-2-1-3-5-18)30-22-8-6-19(16-20(21)22)7-9-23(28)25-29/h1-9,16,29H,10-15,17H2,(H,25,28)
Affinity DataIC50: 130nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair