BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 26 hits   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440120
PNG
(CHEMBL1393516)
Show SMILES Nc1nnc(o1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C8H6ClN3O/c9-6-3-1-5(2-4-6)7-11-12-8(10)13-7/h1-4H,(H2,10,12)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 2.00E+5n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440134
PNG
(CHEMBL2426244)
Show SMILES CCCCCCCc1nc2ccccc2c(O)c1O
Show InChI InChI=1S/C16H21NO2/c1-2-3-4-5-6-11-14-16(19)15(18)12-9-7-8-10-13(12)17-14/h7-10,19H,2-6,11H2,1H3,(H,17,18)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/an/a 210n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440122
PNG
(CHEMBL2426235)
Show SMILES Cc1cccc(c1)-c1nnc(N)o1
Show InChI InChI=1S/C9H9N3O/c1-6-3-2-4-7(5-6)8-11-12-9(10)13-8/h2-5H,1H3,(H2,10,12)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5.78E+4n/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440123
PNG
(CHEMBL2426234)
Show SMILES Nc1nnc(o1)-c1cccc(OC(F)(F)F)c1
Show InChI InChI=1S/C9H6F3N3O2/c10-9(11,12)17-6-3-1-2-5(4-6)7-14-15-8(13)16-7/h1-4H,(H2,13,15)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 4.65E+4n/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440124
PNG
(CHEMBL2426232)
Show SMILES Nc1nnc(o1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C9H6F3N3O/c10-9(11,12)6-3-1-2-5(4-6)7-14-15-8(13)16-7/h1-4H,(H2,13,15)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.85E+4n/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in pqs gene-deficient Pseudomonas aeruginosa PA14 by beta-galactosidase reporter ge...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440125
PNG
(CHEMBL2426228)
Show SMILES Nc1nnc(o1)-c1cccc(Cl)c1
Show InChI InChI=1S/C8H6ClN3O/c9-6-3-1-2-5(4-6)7-11-12-8(10)13-7/h1-4H,(H2,10,12)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.67E+4n/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440126
PNG
(CHEMBL2426233)
Show SMILES Nc1nnc(o1)-c1cccc(c1)C#N
Show InChI InChI=1S/C9H6N4O/c10-5-6-2-1-3-7(4-6)8-12-13-9(11)14-8/h1-4H,(H2,11,13)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.78E+4n/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440127
PNG
(CHEMBL2426238)
Show SMILES Cc1nnc(o1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C10H7F3N2O/c1-6-14-15-9(16-6)7-3-2-4-8(5-7)10(11,12)13/h2-5H,1H3
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.29E+4n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440122
PNG
(CHEMBL2426235)
Show SMILES Cc1cccc(c1)-c1nnc(N)o1
Show InChI InChI=1S/C9H9N3O/c1-6-3-2-4-7(5-6)8-11-12-9(10)13-8/h2-5H,1H3,(H2,10,12)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.24E+4n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440128
PNG
(CHEMBL1545380)
Show SMILES FC(F)(F)c1cc(n[nH]1)-c1cccs1
Show InChI InChI=1S/C8H5F3N2S/c9-8(10,11)7-4-5(12-13-7)6-2-1-3-14-6/h1-4H,(H,12,13)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 1.07E+4n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM98803
PNG
(US8487093, 193)
Show SMILES Nc1cccc(Br)n1
Show InChI InChI=1S/C5H5BrN2/c6-4-2-1-3-5(7)8-4/h1-3H,(H2,7,8)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEBI
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 1.00E+4n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440128
PNG
(CHEMBL1545380)
Show SMILES FC(F)(F)c1cc(n[nH]1)-c1cccs1
Show InChI InChI=1S/C8H5F3N2S/c9-8(10,11)7-4-5(12-13-7)6-2-1-3-14-6/h1-4H,(H,12,13)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 8.50E+3n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50106197
PNG
(3-Bromo-benzamide | CHEMBL122690)
Show SMILES NC(=O)c1cccc(Br)c1
Show InChI InChI=1S/C7H6BrNO/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H2,9,10)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/a 7.60E+3n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440124
PNG
(CHEMBL2426232)
Show SMILES Nc1nnc(o1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C9H6F3N3O/c10-9(11,12)6-3-1-2-5(4-6)7-14-15-8(13)16-7/h1-4H,(H2,13,15)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 7.50E+3n/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440129
PNG
(CHEMBL2426231)
Show SMILES Nc1nnc(o1)-c1cccc(Br)c1
Show InChI InChI=1S/C8H6BrN3O/c9-6-3-1-2-5(4-6)7-11-12-8(10)13-7/h1-4H,(H2,10,12)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 7.50E+3n/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM98803
PNG
(US8487093, 193)
Show SMILES Nc1cccc(Br)n1
Show InChI InChI=1S/C5H5BrN2/c6-4-2-1-3-5(7)8-4/h1-3H,(H2,7,8)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEBI
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 6.80E+3n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50106197
PNG
(3-Bromo-benzamide | CHEMBL122690)
Show SMILES NC(=O)c1cccc(Br)c1
Show InChI InChI=1S/C7H6BrNO/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H2,9,10)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/a 6.80E+3n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440121
PNG
(CHEMBL2426237)
Show SMILES FC(F)(F)c1cccc(c1)-c1nnco1
Show InChI InChI=1S/C9H5F3N2O/c10-9(11,12)7-3-1-2-6(4-7)8-14-13-5-15-8/h1-5H
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 6.50E+3n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440130
PNG
(CHEMBL1383520)
Show SMILES Nc1nnc(s1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C8H6ClN3S/c9-6-3-1-5(2-4-6)7-11-12-8(10)13-7/h1-4H,(H2,10,12)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 4.50E+3n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440130
PNG
(CHEMBL1383520)
Show SMILES Nc1nnc(s1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C8H6ClN3S/c9-6-3-1-5(2-4-6)7-11-12-8(10)13-7/h1-4H,(H2,10,12)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 3.70E+3n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440131
PNG
(CHEMBL2426236)
Show SMILES CC(C)(C)c1cccc(c1)-c1nnc(N)o1
Show InChI InChI=1S/C12H15N3O/c1-12(2,3)9-6-4-5-8(7-9)10-14-15-11(13)16-10/h4-7H,1-3H3,(H2,13,15)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 3.10E+3n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440132
PNG
(CHEMBL154085 | Naphthalene-2-Carboxylic Acid Amide)
Show SMILES NC(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C11H9NO/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,(H2,12,13)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.80E+3n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440124
PNG
(CHEMBL2426232)
Show SMILES Nc1nnc(o1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C9H6F3N3O/c10-9(11,12)6-3-1-2-5(4-6)7-14-15-8(13)16-7/h1-4H,(H2,13,15)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.30E+3n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440133
PNG
(CHEMBL2426225)
Show SMILES CC(C)(C)c1ccc(cc1)C(N)=O
Show InChI InChI=1S/C11H15NO/c1-11(2,3)9-6-4-8(5-7-9)10(12)13/h4-7H,1-3H3,(H2,12,13)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 900n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (lamda DE3) by isothermal titrati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440132
PNG
(CHEMBL154085 | Naphthalene-2-Carboxylic Acid Amide)
Show SMILES NC(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C11H9NO/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,(H2,12,13)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 800n/an/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Binding affinity to Pseudomonas aeruginosa PA14 biotinylated His6SUMO-tagged PqsR expressed in Eschericia coli BL21 (DE3) by surface plasmon resonanc...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair
Transcriptional regulator MvfR


(Pseudomonas aeruginosa PA14)
BDBM50440121
PNG
(CHEMBL2426237)
Show SMILES FC(F)(F)c1cccc(c1)-c1nnco1
Show InChI InChI=1S/C9H5F3N2O/c10-9(11,12)7-3-1-2-6(4-7)8-14-13-5-15-8/h1-5H
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.01E+5n/an/an/an/a



Helmholtz-Institute for Pharmaceutical Research Saarland

Curated by ChEMBL


Assay Description
Antagonist activity at Pseudomonas aeruginosa PA14 PqsR expressed in Eschericia coli DH5-alpha assessed as inhibition of PQS-induced protein activati...


J Med Chem 56: 6761-74 (2013)


Article DOI: 10.1021/jm400830r
BindingDB Entry DOI: 10.7270/Q2T72JV2
More data for this
Ligand-Target Pair