Found 6 of ic50 data for polymerid = 8284 TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]-L-AP4 from rat mGluR8More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat mGlu8 expressed in HEK cells co-expressing Galpha15 assessed as reduction in L-AP4-induced intracellular calcium flux pret...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as decrease in glutamate-induced thallium...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu8 receptor expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux p...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu8 receptor expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux p...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
