TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of rhodesainMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesiense MVAT4 rhodesain expressed in Pichia pastoris using Z-FR-AMC as substrate by fluorometryMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of rhodesainMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Leishmania donovani cysteine proteaseMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assayMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve
Curated by ChEMBL
University Of Algarve
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain 3More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of rhodesainMore data for this Ligand-Target Pair
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve
Curated by ChEMBL
University Of Algarve
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assayMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assayMore data for this Ligand-Target Pair
TargetCysteine protease falcipain-3 [5-492](Plasmodium falciparum)
University Of Algarve
Curated by ChEMBL
University Of Algarve
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of falcipain3More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:Inhibition of ATG4B (unknown origin) using FRETGATE-16 as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by fluorescence techniqueMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:Inhibition of ATG4B (unknown origin) using FRETGATE-16 as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assayMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 145nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of Leishmania donovani cysteine proteaseMore data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development
Curated by ChEMBL
Roche Pharma Research And Early Development
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas
Curated by ChEMBL
Federal University Of Alagoas
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair