Found 1742 Enz. Inhib. hit(s) with Target = 'Insulin receptor' 
Affinity DataKd: 0.0200nMAssay Description:Displacement of [TyrA14-125I]-human insulin from human insulin receptor isoform A expressed in baby hamster kidney cells after 2 days by gamma counti...More data for this Ligand-Target Pair
Affinity DataKd: 1.70nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 6.20nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 8.60nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to human InsR expressed in mouse IGF1R knockout MEF cells assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 53nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 72nMAssay Description:Binding affinity to human INSR by Ambit titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 73nMAssay Description:Average Binding Constant for INSR; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 81nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 81nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 110nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 110nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 110nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
TargetInsulin receptor substrate 1 [1-264](Homo sapiens (Human))
The University Of Texas System
US Patent
The University Of Texas System
US Patent
Affinity DataKd: 140nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Average Binding Constant for INSR; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 190nMAssay Description:Binding affinity to human INSR (997 to 1318 residues) expressed in mammalian expression system by kinome scan-based assayMore data for this Ligand-Target Pair
Affinity DataKd: 210nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 276nMAssay Description:Binding affinity to human IRRMore data for this Ligand-Target Pair
Affinity DataKd: 290nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 290nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 330nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 340nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
TargetInsulin receptor substrate 1 [1-264](Homo sapiens (Human))
The University Of Texas System
US Patent
The University Of Texas System
US Patent
Affinity DataKd: 390nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 400nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 420nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 430nMAssay Description:Binding affinity to INSRRMore data for this Ligand-Target Pair
Affinity DataKd: 430nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 430nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Binding affinity to INSRMore data for this Ligand-Target Pair
Affinity DataKd: 506nMAssay Description:Binding affinity to human INSRMore data for this Ligand-Target Pair
TargetInsulin receptor substrate 1 [1-264](Homo sapiens (Human))
The University Of Texas System
US Patent
The University Of Texas System
US Patent
Affinity DataKd: 520nMAssay Description:KT1 PH domain small molecule inhibitors were identified using the crystal structure of the AKT1 PH domain bound by PtdIns(1,3,4,5)P4 as descried in T...More data for this Ligand-Target Pair
Affinity DataKd: 600nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 630nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 630nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 630nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 850nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMAssay Description:Binding affinity to INSRMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
