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Found 3 Enz. Inhib. hit(s) with all data for entry = 8932
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM430025(4-(4′-Ethanesulfonyl-6-fluoro-2′-metho...)
Affinity DataKi: <0.600nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM430027(5-[5-(1-Ethyl-1H-pyrazolo[3,4-c]pyridazin-4-yl)-2-...)
Affinity DataKi:  11.8nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM430026(4-(4′-Ethanesulfonyl-6-fluorobiphenyl-3-yl)-...)
Affinity DataKi:  17.5nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent