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Found 4 Enz. Inhib. hit(s) with all data for entry = 8910
TargetBeta-lactamase()
Fedora Pharmaceuticals

US Patent
LigandPNGBDBM428643(US10544146, Ex. 40)
Affinity DataIC50:  8nMAssay Description:he inhibitory activities of present compounds against various enzymes were measured by spectrophotometric assay using 490 nM and using nitrocefin as ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase TEM(Escherichia coli)
Fedora Pharmaceuticals

US Patent
LigandPNGBDBM428643(US10544146, Ex. 40)
Affinity DataIC50:  52nMAssay Description:he inhibitory activities of present compounds against various enzymes were measured by spectrophotometric assay using 490 nM and using nitrocefin as ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbapenem-hydrolyzing beta-lactamase KPC()
Fedora Pharmaceuticals

US Patent
LigandPNGBDBM428643(US10544146, Ex. 40)
Affinity DataIC50:  91nMAssay Description:he inhibitory activities of present compounds against various enzymes were measured by spectrophotometric assay using 490 nM and using nitrocefin as ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase()
Fedora Pharmaceuticals

US Patent
LigandPNGBDBM428643(US10544146, Ex. 40)
Affinity DataIC50:  327nMAssay Description:he inhibitory activities of present compounds against various enzymes were measured by spectrophotometric assay using 490 nM and using nitrocefin as ...More data for this Ligand-Target Pair
In DepthDetails US Patent