Compile Data Set for Download or QSAR
maximum 50k data
Found 72 Enz. Inhib. hit(s) with all data for entry = 10407
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM533479((Z)-7-((1R,2S,3R,4S)-4-(2-(2-amino- 3-chloroquinol...)
Affinity DataIC50:  0.200nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533464((E)-7-((2R,3R,4S,5S)-5-((1R)-1-(3,4- dichlorocyclo...)
Affinity DataIC50:  0.200nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533440((2R,3S,4R,5R)-2-((R)-(3,4- dichlorophenyl)(hydroxy...)
Affinity DataIC50:  0.300nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533482((Z)-7-((1R,2S,3R,4S)-4-(2-(2- ((cyclopropylmethyl)...)
Affinity DataIC50:  0.330nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533414(7-((2R,3R,4S,5R)-5-((R)-(3,4- dichlorophenyl)(hydr...)
Affinity DataIC50:  0.400nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533415(7-((2R,3R,4S,5R)-5-((R)-(3,4- difluorophenyl)(hydr...)
Affinity DataIC50:  0.600nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533402((2R,3S,4R,5R)-2-((R)-(4- chlorophenyl)(hydroxy)met...)
Affinity DataIC50:  0.600nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533478((Z)-7-((1R,2S,3R,4S)-4-(2-(2- aminoquinolin-7-yl)e...)
Affinity DataIC50:  0.640nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533439(7-((2R,3R,4S,5R)-5-((R)-(4-chloro-3- methylphenyl)...)
Affinity DataIC50:  0.700nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533408(7-((2R,3R,4S,5R)-5-((R)-(4-chloro-3- fluorophenyl)...)
Affinity DataIC50:  0.700nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533486((Z)-7-((1R,2S,3R,4S)-4-(2-(2- ((cyclopropylmethyl)...)
Affinity DataIC50:  0.820nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533494((2R,3R,4S,5S)-2-(4-amino-5-fluoro-7H- pyrrolo[2,3-...)
Affinity DataIC50:  0.900nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533498((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  0.900nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533497((2R,3R,4S,5S)-2-(4-amino-5-fluoro-7H- pyrrolo[2,3-...)
Affinity DataIC50:  1nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533419(7-((2R,3R,4S,5R)-5-((R)-(3,4- dichlorophenyl)(hydr...)
Affinity DataIC50:  1.80nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533412(7-((2R,3R,4S,5R)-5-((R)-(3-chloro-4- fluorophenyl)...)
Affinity DataIC50:  1.90nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533490((E)-7-((1R,2S,3R,4R)-4-((S)-(3,4- dichlorophenyl)(...)
Affinity DataIC50:  2.30nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533404(7-((2R,3R,4S,5R)-5-((R)-(4- chlorophenyl)(hydroxy)...)
Affinity DataIC50:  2.40nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533455((E)-7-((2R,3R,4S,5S)-5-((R)-1-(3,4- dichlorophenyl...)
Affinity DataIC50:  2.40nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533434(7-((2R,3R,4S,5S)-5-((R)-1-(3,4- dichlorophenyl)-1-...)
Affinity DataIC50:  2.60nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533477((Z)-7-((1R,2S,3R,4S)-2,3-dihydroxy- 4-(2-(2-(methy...)
Affinity DataIC50:  2.70nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533430((2R,3R,4S,5R)-2-(4-hydrazineylidene-1,4- dihydro-7...)
Affinity DataIC50:  2.70nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533424(7-((2R,3R,4S,5R)-5-((R)-(4- chlorophenyl)(hydroxy)...)
Affinity DataIC50:  2.80nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533421(7-((2R,3R,4S,5S)-5-((R)-1-(4-chlorophenyl)-1- hydr...)
Affinity DataIC50:  2.80nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533433(7-((2R,3R,4S,5R)-5-((R)-(3-fluoro-4- (trifluoromet...)
Affinity DataIC50:  3.10nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533488((1S,2R,3S,5R)-3-(2-(2- ((cyclopropylmethyl)amino)q...)
Affinity DataIC50:  3.20nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533491((E)-7-((1R,2S,3R,4S)-4-((S)-1-(3,4- dichlorophenyl...)
Affinity DataIC50:  3.40nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533492((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)- 5-((R)-1-...)
Affinity DataIC50:  3.60nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533442(7-((2R,3R,4S,5R)-5-((R)-(3,4- dichlorophenyl)(hydr...)
Affinity DataIC50:  3.90nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533473((1S,2R,3R,5R)-3-((S)-(3,4- difluorophenyl)(hydroxy...)
Affinity DataIC50:  6.30nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533495((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  6.90nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533476((1S,2R,3S,5R)-3-(2-(2- ((cyclopropylmethyl)amino)q...)
Affinity DataIC50:  8.20nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533409((2R,3S,4R,5R)-2-((R)-(4- chlorophenyl)(hydroxy)met...)
Affinity DataIC50:  8.30nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533454((Z)-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-((R)- hydroxy...)
Affinity DataIC50:  8.40nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533407(7-((2R,3R,4S,5R)-5-((R)-(4-chloro-3- fluorophenyl)...)
Affinity DataIC50:  8.60nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533469((Z)-9-((2R,3R,4S,5S)-5-((R)-1-(3,4- dichlorophenyl...)
Affinity DataIC50:  9.60nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533425((2R,3S,4R,5R)-2-((R)-(4- chlorophenyl)(hydroxy)met...)
Affinity DataIC50:  9.70nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533463((Z)-7-((2R,3R,4S,5R)-5-((R)-(3,4- dichlorophenyl)(...)
Affinity DataIC50:  10.2nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533420(7-((2R,3R,4S,5R)-5-((R)-(3,4- difluorophenyl)(hydr...)
Affinity DataIC50:  10.2nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533475((E)-7-((1R,2S,3R,4R)-4-((S)-(4- chlorophenyl)(hydr...)
Affinity DataIC50:  11.7nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533493((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)- 5-((R)-1-...)
Affinity DataIC50:  13.5nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533422(7-((2R,3R,4S,5R)-5-((R)-(4- chlorophenyl)(hydroxy)...)
Affinity DataIC50:  13.9nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533489((Z)-7-((1R,2S,3R,4R)-4-((S)-(3,4- dichlorophenyl)(...)
Affinity DataIC50:  19.9nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533410(9-((2R,3R,4S,5R)-5-((R)-(4- chlorophenyl)(hydroxy)...)
Affinity DataIC50:  25.6nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533468((Z)-7-((2R,3R,4S,5S)-5-((R)-1-(3,4- dichlorophenyl...)
Affinity DataIC50:  28nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533443(7-((2R,3R,4S)-5-((R)-1-(4-chlorophenyl)-1- hydroxy...)
Affinity DataIC50:  29.1nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533461((Z)-7-((2R,3R,4S,5R)-5-((R)-(3,4- dichlorophenyl)(...)
Affinity DataIC50:  29.6nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
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TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
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US Patent
LigandPNGBDBM533417(7-((2R,3R,4S,5R)-5-((R)-(3-chloro-4- fluorophenyl)...)
Affinity DataIC50:  35nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM533495((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo[2,3-d]pyrimid...)
Affinity DataIC50:  37nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM533484((Z)-7-((1R,2S,3R,4R)-4-((S)-(3,4- difluorophenyl)(...)
Affinity DataIC50:  37nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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