Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 6300
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121019(US8722721, 11)
Affinity DataIC50:  2.40nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121018(US8722721, 10)
Affinity DataIC50:  3.70nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121011(US8722721, 2)
Affinity DataIC50:  16.2nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121027(US8722721, 7)
Affinity DataIC50:  42.1nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121014(US8722721, 5 | US8722721, 6)
Affinity DataIC50:  66.4nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121010(US8722721, 1)
Affinity DataIC50:  67nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121017(US8722721, 9)
Affinity DataIC50:  73.3nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121023(US8722721, 15)
Affinity DataIC50:  136nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121014(US8722721, 5 | US8722721, 6)
Affinity DataIC50:  158nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121024(US8722721, 16)
Affinity DataIC50:  175nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121026(US8722721, 18)
Affinity DataIC50:  185nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121012(US8722721, 3)
Affinity DataIC50:  189nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121013(US8722721, 4)
Affinity DataIC50:  198nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121016(US8722721, 8)
Affinity DataIC50:  343nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121020(US8722721, 12)
Affinity DataIC50:  350nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121022(US8722721, 14)
Affinity DataIC50:  422nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121021(US8722721, 13)
Affinity DataIC50:  994nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM121025(US8722721, 17)
Affinity DataIC50:  1.07E+3nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent