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Found 17 Enz. Inhib. hit(s) with all data for entry = 7012
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166433(US9073833, 1)
Affinity DataIC50:  30nMT: 2°CAssay Description:Each of Compounds (1) to (6) was dissolved in 100% DMSO so as to obtain stock to compound solutions with concentrations of 0.01, 0.03, 0.1, 0.3, 1, 3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166439(US9073833, Sivelestat)
Affinity DataIC50:  50nMT: 2°CAssay Description:Each of Compounds (1) to (6) was dissolved in 100% DMSO so as to obtain stock to compound solutions with concentrations of 0.01, 0.03, 0.1, 0.3, 1, 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166436(US9073833, 4)
Affinity DataIC50:  80nMT: 2°CAssay Description:Each of Compounds (1) to (6) was dissolved in 100% DMSO so as to obtain stock to compound solutions with concentrations of 0.01, 0.03, 0.1, 0.3, 1, 3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166434(US9073833, 2)
Affinity DataIC50:  110nMT: 2°CAssay Description:Each of Compounds (1) to (6) was dissolved in 100% DMSO so as to obtain stock to compound solutions with concentrations of 0.01, 0.03, 0.1, 0.3, 1, 3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166435(US9073833, 3)
Affinity DataIC50:  130nMT: 2°CAssay Description:Each of Compounds (1) to (6) was dissolved in 100% DMSO so as to obtain stock to compound solutions with concentrations of 0.01, 0.03, 0.1, 0.3, 1, 3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166437(US9073833, 5)
Affinity DataIC50:  170nMT: 2°CAssay Description:Each of Compounds (1) to (6) was dissolved in 100% DMSO so as to obtain stock to compound solutions with concentrations of 0.01, 0.03, 0.1, 0.3, 1, 3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166438(US9073833, 6)
Affinity DataIC50:  180nMT: 2°CAssay Description:Each of Compounds (1) to (6) was dissolved in 100% DMSO so as to obtain stock to compound solutions with concentrations of 0.01, 0.03, 0.1, 0.3, 1, 3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166433(US9073833, 1)
Affinity DataIC50:  5.13E+4nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166439(US9073833, Sivelestat)
Affinity DataIC50:  6.50E+4nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166440(US9073833, 7)
Affinity DataIC50:  1.59E+5nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166433(US9073833, 1)
Affinity DataIC50:  2.22E+5nMpH: 7.5Assay Description:Compound (1) was mixed with 50 uL of buffer C [containing 100 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES, pH 7.5), 500 mM NaCl, 10%...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166437(US9073833, 5)
Affinity DataIC50:  3.24E+5nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166439(US9073833, Sivelestat)
Affinity DataIC50:  3.38E+5nMpH: 7.5Assay Description:Compound (1) was mixed with 50 uL of buffer C [containing 100 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES, pH 7.5), 500 mM NaCl, 10%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166438(US9073833, 6)
Affinity DataIC50:  3.67E+5nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166435(US9073833, 3)
Affinity DataIC50:  3.68E+5nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166436(US9073833, 4)
Affinity DataIC50:  3.94E+5nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

US Patent
LigandPNGBDBM166434(US9073833, 2)
Affinity DataIC50:  6.79E+5nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair
In DepthDetails US Patent