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Found 28 Enz. Inhib. hit(s) with all data for entry = 7145
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310923(CHEMBL1077943 | US9120807, 6 | {6-Methylamino-2-[(...)
Affinity DataIC50:  1.40nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310925(CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-...)
Affinity DataIC50:  6.5nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310924(CHEMBL1080421 | US9120807, 8 | {6-Ethylamino-2-[(p...)
Affinity DataIC50:  6.70nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310922(CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridi...)
Affinity DataIC50:  7.10nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310925(CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-...)
Affinity DataIC50:  19.4nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3 [I248L](Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310923(CHEMBL1077943 | US9120807, 6 | {6-Methylamino-2-[(...)
Affinity DataIC50:  22.9nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM177999(US9120807, 11)
Affinity DataIC50:  36.7nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3 [I248L](Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310924(CHEMBL1080421 | US9120807, 8 | {6-Ethylamino-2-[(p...)
Affinity DataIC50:  37.3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM177998(US9120807, 10)
Affinity DataIC50:  52.3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310923(CHEMBL1077943 | US9120807, 6 | {6-Methylamino-2-[(...)
Affinity DataIC50:  57.6nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50:  68.9nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310924(CHEMBL1080421 | US9120807, 8 | {6-Ethylamino-2-[(p...)
Affinity DataIC50:  118nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3 [I248L](Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310925(CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-...)
Affinity DataIC50:  130nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM177998(US9120807, 10)
Affinity DataIC50:  161nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM177999(US9120807, 11)
Affinity DataIC50:  216nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3 [I248L](Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310922(CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridi...)
Affinity DataIC50:  233nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50:  256nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310923(CHEMBL1077943 | US9120807, 6 | {6-Methylamino-2-[(...)
Affinity DataIC50:  277nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3 [I248L](Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50:  308nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310925(CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-...)
Affinity DataIC50:  318nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3 [I248L](Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM177999(US9120807, 11)
Affinity DataIC50:  361nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310924(CHEMBL1080421 | US9120807, 8 | {6-Ethylamino-2-[(p...)
Affinity DataIC50:  726nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3 [I248L](Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM177998(US9120807, 10)
Affinity DataIC50:  747nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50:  828nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310922(CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridi...)
Affinity DataIC50:  1.10E+3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM50310922(CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridi...)
Affinity DataIC50:  1.40E+3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM177999(US9120807, 11)
Affinity DataIC50:  3.75E+3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

US Patent
LigandPNGBDBM177998(US9120807, 10)
Affinity DataIC50:  3.75E+3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In DepthDetails US Patent