Compile Data Set for Download or QSAR
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Found 10 Enz. Inhib. hit(s) with all data for entry = 7173
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM179542(US9126978, 4)
Affinity DataIC50:  800nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 μM KEA...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM179541(US9126978, 3)
Affinity DataIC50:  860nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 μM KEA...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM179543(US9126978, 5)
Affinity DataIC50:  1.00E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 μM KEA...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM179539(US9126978, 1)
Affinity DataIC50:  1.10E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 μM KEA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM179540(US9126978, 2)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 μM KEA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM179542(US9126978, 4)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM179540(US9126978, 2)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM179543(US9126978, 5)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM179539(US9126978, 1)
Affinity DataIC50: >3.00E+4nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM179541(US9126978, 3)
Affinity DataIC50: >3.00E+4nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In DepthDetails US Patent