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Found 77 Enz. Inhib. hit(s) with all data for entry = 7234
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182767(US9145414, 17 | US9145414, 9)
Affinity DataIC50:  0.210nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182770(US9145414, 26)
Affinity DataIC50:  0.220nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182781(US9145414, 65)
Affinity DataIC50:  0.230nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182789(US9145414, 91)
Affinity DataIC50:  0.260nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182806(US9145414, 220)
Affinity DataIC50:  0.260nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182783(US9145414, 67)
Affinity DataIC50:  0.260nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182774(US9145414, 48)
Affinity DataIC50:  0.270nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182798(US9145414, 161)
Affinity DataIC50:  0.280nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182810(US9145414, 258)
Affinity DataIC50:  0.290nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182799(US9145414, 164)
Affinity DataIC50:  0.290nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182805(US9145414, 212)
Affinity DataIC50:  0.290nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182820(US9145414, 316)
Affinity DataIC50:  0.310nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182811(US9145414, 259)
Affinity DataIC50:  0.330nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182804(US9145414, 209)
Affinity DataIC50:  0.330nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182778(US9145414, 60)
Affinity DataIC50:  0.330nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182817(US9145414, 284)
Affinity DataIC50:  0.340nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182808(US9145414, 256)
Affinity DataIC50:  0.350nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182807(US9145414, 245)
Affinity DataIC50:  0.350nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182800(US9145414, 165)
Affinity DataIC50:  0.360nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182763(US9145414, 3)
Affinity DataIC50:  0.360nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182769(US9145414, 25)
Affinity DataIC50:  0.360nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182779(US9145414, 61)
Affinity DataIC50:  0.370nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182788(US9145414, 79)
Affinity DataIC50:  0.370nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182822(US9145414, 359)
Affinity DataIC50:  0.370nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182784(US9145414, 73)
Affinity DataIC50:  0.370nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182780(US9145414, 62)
Affinity DataIC50:  0.370nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182797(US9145414, 160)
Affinity DataIC50:  0.380nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182802(US9145414, 184)
Affinity DataIC50:  0.380nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182809(US9145414, 257)
Affinity DataIC50:  0.380nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182791(US9145414, 97)
Affinity DataIC50:  0.390nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182803(US9145414, 208)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182761(US9145414, 1)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182813(US9145414, 267)
Affinity DataIC50:  0.410nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182815(US9145414, 277)
Affinity DataIC50:  0.410nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182793(US9145414, 100)
Affinity DataIC50:  0.410nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182775(US9145414, 50)
Affinity DataIC50:  0.420nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182772(US9145414, 34)
Affinity DataIC50:  0.420nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182786(US9145414, 77)
Affinity DataIC50:  0.420nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182796(US9145414, 154)
Affinity DataIC50:  0.430nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182762(US9145414, 2)
Affinity DataIC50:  0.460nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182764(US9145414, 11)
Affinity DataIC50:  0.470nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182816(US9145414, 282)
Affinity DataIC50:  0.480nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182765(US9145414, 13)
Affinity DataIC50:  0.490nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182776(US9145414, 56)
Affinity DataIC50:  0.5nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182812(US9145414, 265)
Affinity DataIC50:  0.5nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182773(US9145414, 35)
Affinity DataIC50:  0.510nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182777(US9145414, 57)
Affinity DataIC50:  0.520nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM60658(US9145414, 5)
Affinity DataIC50:  0.520nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibitory activity of the compound against Aurora B kinase activity was assayed with reference to a method described in patent public...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182787(US9145414, 78)
Affinity DataIC50:  0.530nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182768(US9145414, 24)
Affinity DataIC50:  0.530nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
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