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Found 5 Enz. Inhib. hit(s) for PDB: 2BDJ
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM50314074(2,6,9-Trisubstitute purine, 6 (AP23464) | 3-(2-(2-...)
Affinity DataIC50:  0.450nMpH: 7.4 T: 2°CAssay Description:Inhibition of human Src kinase activity by ARIAD compounds were measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM50314074(2,6,9-Trisubstitute purine, 6 (AP23464) | 3-(2-(2-...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of 6x-His-tagged human Src kinase domain (T250 to L536 residues) expressed in Sf9 cells incubated for 2 hrs in presence of biotinylated cd...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM50314074(2,6,9-Trisubstitute purine, 6 (AP23464) | 3-(2-(2-...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM50314074(2,6,9-Trisubstitute purine, 6 (AP23464) | 3-(2-(2-...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

LigandPNGBDBM50314074(2,6,9-Trisubstitute purine, 6 (AP23464) | 3-(2-(2-...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed