Affinity DataIC50: 2.35nMAssay Description:Inhibition of human YES/YES1 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of FYN (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of YES (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 52nMAssay Description:Binding constant for YES kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 52nMAssay Description:Binding constant for YES kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 33nMAssay Description:Binding constant for FYN kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 51nMAssay Description:Average Binding Constant for FYN; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 49nMAssay Description:Average Binding Constant for YES; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 33nMAssay Description:Binding constant for FYN kinase domainMore data for this Ligand-Target Pair