Found 9 Enz. Inhib. hit(s) for PDB: 4A50 TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
3D Structure (crystal)TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 6.40nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 7.10nMAssay Description:Inhibition of MT-stimulated human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain ATPase activity expressed in Escherichia col...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 10.2nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 11.1nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 12.2nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 12.8nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataEC50: 73nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
