Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50008491
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058855((S)-2-Butoxycarbonylamino-3-{2-[(R)-3-(4-carbamimi...)
Affinity DataIC50:  0.25nMAssay Description:Inhbition of platelet aggregation in heparin treated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073814(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  0.550nMAssay Description:Inhbition of platelet aggregation in heparin treated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073819(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  0.860nMAssay Description:Inhibition of platelet aggregation in citrated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055896(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of fibrinogen (Fg) interaction with GPIIb/IIIa in gel filtered plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073820(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  1.20nMAssay Description:Affinity for purified human platelet glycoprotein alpha IIb beta3 integrin receptor in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073818(2-(Bis-allyloxy-phosphorylamino)-3-{2-[3-(4-carbam...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of fibrinogen (Fg) interaction with GPIIb/IIIa in gel filtered plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073817(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of fibrinogen (Fg) interaction with GPIIb/IIIa in gel filtered plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073815(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of fibrinogen (Fg) interaction with GPIIb/IIIa in gel filtered plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058855((S)-2-Butoxycarbonylamino-3-{2-[(R)-3-(4-carbamimi...)
Affinity DataIC50:  21nMAssay Description:Affinity for purified human platelet glycoprotein alpha IIb beta3 integrin receptor in ELISAMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073818(2-(Bis-allyloxy-phosphorylamino)-3-{2-[3-(4-carbam...)
Affinity DataIC50:  46nMAssay Description:Inhibition of fibrinogen (Fg) interaction with GPIIb/IIIa in gel filtered plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058855((S)-2-Butoxycarbonylamino-3-{2-[(R)-3-(4-carbamimi...)
Affinity DataIC50:  50nMAssay Description:Inhibition of fibrinogen (Fg) interaction with GPIIb/IIIa in gel filtered plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073814(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  54nMAssay Description:Inhibition of platelet aggregation in citrated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073820(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  55nMAssay Description:Affinity for purified human platelet glycoprotein alpha IIb beta3 integrin receptor in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058855((S)-2-Butoxycarbonylamino-3-{2-[(R)-3-(4-carbamimi...)
Affinity DataIC50:  66nMAssay Description:Inhbition of platelet aggregation in heparin treated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073819(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  73nMAssay Description:Inhibition of fibrinogen (Fg) interaction with GPIIb/IIIa in gel filtered plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073817(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  102nMAssay Description:Affinity for purified human platelet glycoprotein alpha IIb beta3 integrin receptor in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073819(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  103nMAssay Description:Inhibition of platelet aggregation in citrated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073814(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  105nMAssay Description:Inhbition of platelet aggregation in heparin treated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073820(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  114nMAssay Description:Inhibition of platelet aggregation in citrated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073817(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  117nMAssay Description:Affinity for purified human platelet glycoprotein alpha IIb beta3 integrin receptor in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073818(2-(Bis-allyloxy-phosphorylamino)-3-{2-[3-(4-carbam...)
Affinity DataIC50:  122nMAssay Description:Inhibition of platelet aggregation in citrated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055896(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  140nMAssay Description:Affinity for purified human platelet glycoprotein alpha IIb beta3 integrin receptor in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073814(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  197nMAssay Description:Inhbition of platelet aggregation in heparin treated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073819(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  210nMAssay Description:Inhbition of platelet aggregation in heparin treated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073820(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  221nMAssay Description:Inhbition of platelet aggregation in heparin treated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073818(2-(Bis-allyloxy-phosphorylamino)-3-{2-[3-(4-carbam...)
Affinity DataIC50:  224nMAssay Description:Affinity for purified human platelet glycoprotein alpha IIb beta3 integrin receptor in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073815(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  229nMAssay Description:Inhibition of platelet aggregation in citrated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055896(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  240nMAssay Description:Inhibition of platelet aggregation in citrated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073817(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  240nMAssay Description:Inhibition of platelet aggregation in citrated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073815(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  260nMAssay Description:Inhibition of fibrinogen (Fg) interaction with GPIIb/IIIa in gel filtered plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073815(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  376nMAssay Description:Affinity for purified human platelet glycoprotein alpha IIb beta3 integrin receptor in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055896(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  560nMAssay Description:Inhbition of platelet aggregation in heparin treated human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed