Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 50035038
TargetProthrombin(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075822((S)-N-[1-(1-Amino-isoquinolin-6-ylmethyl)-2-oxo-2-...)
Affinity DataIC50:  82nMAssay Description:Compound was tested for inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataIC50:  169nMAssay Description:Compound was tested for inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataIC50:  690nMAssay Description:Compound was tested for inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075824(Aminoisoquinoline derivative | CHEMBL351865)
Affinity DataIC50:  1.10E+3nMAssay Description:Compound was tested for inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075826(CHEMBL350114 | N-[1-(1-Amino-isoquinolin-6-ylmethy...)
Affinity DataIC50:  2.80E+4nMAssay Description:Compound was tested for inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075823(CHEMBL159435 | N-[1-(1-Amino-isoquinolin-6-ylmethy...)
Affinity DataIC50:  5.50E+4nMAssay Description:Compound was tested for inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075823(CHEMBL159435 | N-[1-(1-Amino-isoquinolin-6-ylmethy...)
Affinity DataIC50:  2.55E+5nMAssay Description:Compound was tested for inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075825(CHEMBL162185 | N-[1-(1-Amino-isoquinolin-6-ylmethy...)
Affinity DataIC50:  3.57E+5nMAssay Description:Compound was tested for inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075822((S)-N-[1-(1-Amino-isoquinolin-6-ylmethyl)-2-oxo-2-...)
Affinity DataIC50:  3.78E+5nMAssay Description:Compound was tested for inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed