Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50008739
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi:  5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076730((S)-5-(4-Methylamino-phenyl)-2-(4-propyl-benzenesu...)
Affinity DataKi:  8nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076724((S)-5-(4-Methylamino-phenyl)-2-(naphthalene-2-sulf...)
Affinity DataKi:  19nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076725((S)-2-(6-Methoxy-naphthalene-2-sulfonylamino)-5-(4...)
Affinity DataKi:  27nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076723((S)-5-(3-Amino-4-methylamino-phenyl)-2-(naphthalen...)
Affinity DataKi:  40nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076728((S)-5-(3,4-Diamino-phenyl)-2-(naphthalene-2-sulfon...)
Affinity DataKi:  220nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076737((S)-5-(4-Amino-phenyl)-2-(naphthalene-2-sulfonylam...)
Affinity DataKi:  290nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076721((S)-5-(6-Methylamino-pyridin-3-yl)-2-(naphthalene-...)
Affinity DataKi:  300nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076738((S)-5-(6-Amino-pyridin-3-yl)-2-(naphthalene-2-sulf...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076735((S)-5-(4-Hydrazino-phenyl)-2-(naphthalene-2-sulfon...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibitory activity of the compound against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076732((S)-5-(3-Amino-phenyl)-2-(naphthalene-2-sulfonylam...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076731((S)-2-(Naphthalene-2-sulfonylamino)-5-pyridin-3-yl...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076739((S)-5-(1H-Imidazol-4-yl)-2-(naphthalene-2-sulfonyl...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076727((S)-5-(4-Aminomethyl-phenyl)-2-(naphthalene-2-sulf...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076734((S)-5-(2-Methylamino-pyrimidin-5-yl)-2-(naphthalen...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076736((S)-5-(2-Amino-thiazol-5-yl)-2-(naphthalene-2-sulf...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076730((S)-5-(4-Methylamino-phenyl)-2-(4-propyl-benzenesu...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibitory activity of the compound against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076724((S)-5-(4-Methylamino-phenyl)-2-(naphthalene-2-sulf...)
Affinity DataKi:  8.70E+3nMAssay Description:Inhibitory activity of the compound against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076725((S)-2-(6-Methoxy-naphthalene-2-sulfonylamino)-5-(4...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibitory activity of the compound against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076733((S)-2-(Naphthalene-2-sulfonylamino)-5-pyridin-4-yl...)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076726((S)-5-(2-Amino-pyrimidin-5-yl)-2-(naphthalene-2-su...)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory activity of the compound against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076725((S)-2-(6-Methoxy-naphthalene-2-sulfonylamino)-5-(4...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory activity of the compound against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076730((S)-5-(4-Methylamino-phenyl)-2-(4-propyl-benzenesu...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory activity of the compound against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076723((S)-5-(3-Amino-4-methylamino-phenyl)-2-(naphthalen...)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibitory activity of the compound against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076724((S)-5-(4-Methylamino-phenyl)-2-(naphthalene-2-sulf...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibitory activity of the compound against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076729((S)-5-(4-Ethylamino-phenyl)-2-(naphthalene-2-sulfo...)
Affinity DataKi:  4.90E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076730((S)-5-(4-Methylamino-phenyl)-2-(4-propyl-benzenesu...)
Affinity DataKi:  1.90E+5nMAssay Description:Inhibitory activity of the compound against tissue type plasminogen activator (t-PA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076725((S)-2-(6-Methoxy-naphthalene-2-sulfonylamino)-5-(4...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076724((S)-5-(4-Methylamino-phenyl)-2-(naphthalene-2-sulf...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076725((S)-2-(6-Methoxy-naphthalene-2-sulfonylamino)-5-(4...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity of the compound against tissue type plasminogen activator (t-PA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076724((S)-5-(4-Methylamino-phenyl)-2-(naphthalene-2-sulf...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity of the compound against tissue type plasminogen activator (t-PA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076730((S)-5-(4-Methylamino-phenyl)-2-(4-propyl-benzenesu...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibitory activity of the compound against tissue type plasminogen activator (t-PA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed