Compile Data Set for Download or QSAR
maximum 50k data
Found 168 Enz. Inhib. hit(s) with all data for entry = 50009358
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082446(7-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50:  1nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082459(CHEMBL140543 | [2-(4'-Dimethylamino-biphenyl-4-sul...)
Affinity DataIC50:  1nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082476(2-(4-Butoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-is...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082501(2-(Biphenyl-4-sulfonyl)-1,2,3,4-tetrahydro-isoquin...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082511(2-[4-(4-Fluoro-benzyloxy)-benzenesulfonyl]-1,2,3,4...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082468(2-(4'-Dimethylamino-biphenyl-4-sulfonyl)-1,2,3,4-t...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082469(2-[4-(4-Dimethylamino-phenoxy)-benzenesulfonyl]-1,...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082507(2-(4-Phenoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-i...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082473(CHEMBL341604 | Carbonic acid ethyl ester 3-hydroxy...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082499(2-(5-Pyridin-2-yl-thiophen-2-ylmethanesulfonyl)-1,...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082496(7-Amino-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082490(7-Amino-2-(4'-fluoro-biphenyl-4-sulfonyl)-1,2,3,4-...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082474(CHEMBL138613 | {(S)-1-[3-Hydroxycarbamoyl-2-(4-met...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082458(2-(4-Benzoyl-benzenesulfonyl)-1,2,3,4-tetrahydro-i...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082477(CHEMBL138953 | [3-Hydroxycarbamoyl-2-(4-methoxy-be...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082497(2-(4'-Chloro-biphenyl-4-sulfonyl)-1,2,3,4-tetrahyd...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077393((R)-5-(4-Methoxy-benzenesulfonyl)-1-methyl-4,5,6,7...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077450((R)-2-(4-Methoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077443((R)-5-(4-Methoxy-benzenesulfonyl)-4,5,6,7-tetrahyd...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082475(7-((S)-2-Amino-propionylamino)-2-(4-methoxy-benzen...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082451(CHEMBL140439 | [7-Amino-2-(4'-chloro-biphenyl-4-su...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077401((R)-2-(4-Phenoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082504(2-(5-Isoxazol-3-yl-thiophene-2-sulfonyl)-1,2,3,4-t...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082492(4-Methoxy-benzenesulfonic acid 3-hydroxycarbamoyl-...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082460(2-(4-Methoxy-benzenesulfonyl)-7-nitro-1,2,3,4-tetr...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082438(CHEMBL141674 | Oxo-[2-(4-phenoxy-benzenesulfonyl)-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082446(7-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082513(CHEMBL141560 | [2-(4'-Fluoro-biphenyl-4-sulfonyl)-...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082502(CHEMBL141038 | Oxo-[2-(4'-trifluoromethyl-biphenyl...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082496(7-Amino-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082455(CHEMBL344410 | [2-(Biphenyl-4-sulfonyl)-1,2,3,4-te...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082464((S)-N-[3-Hydroxycarbamoyl-2-(4-methoxy-benzenesulf...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082494(2-(Dibenzofuran-2-sulfonyl)-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082456(CHEMBL140368 | {2-[4-(4-Cyano-phenoxy)-benzenesulf...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077443((R)-5-(4-Methoxy-benzenesulfonyl)-4,5,6,7-tetrahyd...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082497(2-(4'-Chloro-biphenyl-4-sulfonyl)-1,2,3,4-tetrahyd...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082474(CHEMBL138613 | {(S)-1-[3-Hydroxycarbamoyl-2-(4-met...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082506(CHEMBL424473 | {2-[4-(4-Chloro-phenoxy)-benzenesul...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082507(2-(4-Phenoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-i...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082478(CHEMBL343392 | Sodium; 3-[3-hydroxycarbamoyl-2-(4-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082488(2-(2-Phenyl-ethanesulfonyl)-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082450(CHEMBL142095 | [2-(4'-Chloro-biphenyl-4-sulfonyl)-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082463(2-[5-(2-Methylsulfanyl-pyrimidin-4-yl)-thiophene-2...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082465(CHEMBL335118 | [2-(2-Biphenyl-4-yl-ethanesulfonyl)...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082467(CHEMBL141283 | [2-(4'-Chloro-biphenyl-4-sulfonyl)-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082469(2-[4-(4-Dimethylamino-phenoxy)-benzenesulfonyl]-1,...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082473(CHEMBL341604 | Carbonic acid ethyl ester 3-hydroxy...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082477(CHEMBL138953 | [3-Hydroxycarbamoyl-2-(4-methoxy-be...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082479(2-Benzenesulfonyl-1,2,3,4-tetrahydro-isoquinoline-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077450((R)-2-(4-Methoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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