Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50042162
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50:  79.4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50:  79.4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421427(CHEMBL543228)
Affinity DataIC50:  501nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421417(CHEMBL541346)
Affinity DataIC50:  630nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421425(CHEMBL544872)
Affinity DataIC50:  794nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421423(CHEMBL543939)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421426(CHEMBL552585)
Affinity DataIC50:  3.16E+3nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421420(CHEMBL225385)
Affinity DataIC50:  1.26E+4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421422(CHEMBL543226)
Affinity DataIC50:  1.26E+4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM4313((2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-...)
Affinity DataIC50:  1.26E+4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421418(CHEMBL542522)
Affinity DataIC50:  1.58E+4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM85122(Thr1 inhibitor, 1)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Janus kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibition of Janus kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421424(CHEMBL542762)
Affinity DataIC50:  2.00E+5nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50421421(CHEMBL154693)
Affinity DataIC50:  5.01E+5nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50218571(CHEMBL541100)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50218575(CHEMBL544174)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50218573(CHEMBL542023)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50218574(CHEMBL540593)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50218572(CHEMBL154877)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed