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Found 27 Enz. Inhib. hit(s) with all data for entry = 50011217
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103860(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103862(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)
Affinity DataIC50:  510nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103861(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)
Affinity DataIC50:  820nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103871(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)
Affinity DataIC50:  870nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103858(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103854(2-(3-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103870(2-(3-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103855(2-(3-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103857(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103853(2-(4-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103873(2-(3-{[2-(1H-Benzoimidazol-2-ylmethyl)-3-methyl-3H...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103859(5-(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103851(2-(3-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103868(5-(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103863(4-(Bis-carboxymethyl-carbamoyl)-2-{[2-(5-carbamoyl...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103856(2-(3-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103850(4-(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103864(2-(3-{[2-(1H-Benzoimidazol-2-ylmethyl)-3-methyl-3H...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103849(2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-meth...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103872(2-(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103865(CHEMBL306151 | [4-(2-{[2-(5-Carbamoyl-1H-benzoimid...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103866(2-(4-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103867(3-(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103852(2-(4-((S)-Benzyloxycarbonyl)-4-{[2-(5-carbamoyl-1H...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103869(2-((S)-3-Benzyloxycarbonyl-3-{[2-(5-carbamoyl-1H-b...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103874(4-(3-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)...)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease in the presence of Zn2+.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103860(2-{[2-(5-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)
Affinity DataIC50:  1.67E+5nMAssay Description:Inhibitory activity of the compound against hepatitis C virus (HCV) NS3 protease in the absence of Zn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed