Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50011281
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104592((S)-3-{[3-(2-Piperidin-4-yl-ethyl)-5,6,7,8-tetrahy...)
Affinity DataIC50:  0.0160nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104598(2-Benzyloxycarbonylamino-3-{[(R)-1-(3-piperidin-4-...)
Affinity DataIC50:  0.0270nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104602(2-Benzyloxycarbonylamino-3-{[3-(2-piperidin-4-yl-v...)
Affinity DataIC50:  0.0410nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104595(2-Phenylmethanesulfonylamino-3-{[3-(2-piperidin-4-...)
Affinity DataIC50:  0.0430nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104591((S)-3-{[3-((E)-2-Piperidin-4-yl-vinyl)-5,6,7,8-tet...)
Affinity DataIC50:  0.0570nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104600((S)-3-{[(R)-1-(3-Piperidin-4-yl-propionyl)-piperid...)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104597((S)-3-{[3-((E)-2-Piperidin-4-yl-vinyl)-5,6,7,8-tet...)
Affinity DataIC50:  0.0610nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104594(2-Benzyloxycarbonylamino-3-{[3-(2-piperidin-4-yl-e...)
Affinity DataIC50:  0.0680nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104596(3-{[3-(2-Piperidin-4-yl-vinyl)-5,6,7,8-tetrahydro-...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104598(2-Benzyloxycarbonylamino-3-{[(R)-1-(3-piperidin-4-...)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104597((S)-3-{[3-((E)-2-Piperidin-4-yl-vinyl)-5,6,7,8-tet...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104602(2-Benzyloxycarbonylamino-3-{[3-(2-piperidin-4-yl-v...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104600((S)-3-{[(R)-1-(3-Piperidin-4-yl-propionyl)-piperid...)
Affinity DataIC50:  0.360nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104599((S)-3-{[3-(2-Piperidin-4-yl-ethyl)-[1,2,4]triazolo...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104591((S)-3-{[3-((E)-2-Piperidin-4-yl-vinyl)-5,6,7,8-tet...)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104594(2-Benzyloxycarbonylamino-3-{[3-(2-piperidin-4-yl-e...)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104595(2-Phenylmethanesulfonylamino-3-{[3-(2-piperidin-4-...)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104592((S)-3-{[3-(2-Piperidin-4-yl-ethyl)-5,6,7,8-tetrahy...)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104590(2-Isobutoxycarbonylamino-3-{[3-(2-piperidin-4-yl-v...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104590(2-Isobutoxycarbonylamino-3-{[3-(2-piperidin-4-yl-v...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104596(3-{[3-(2-Piperidin-4-yl-vinyl)-5,6,7,8-tetrahydro-...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104593(2-Benzyloxycarbonylamino-3-{[8-methyl-3-(2-piperid...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104599((S)-3-{[3-(2-Piperidin-4-yl-ethyl)-[1,2,4]triazolo...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104593(2-Benzyloxycarbonylamino-3-{[8-methyl-3-(2-piperid...)
Affinity DataIC50:  18nMAssay Description:Inhibition of thrombin-induced human gel-filtered platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104601((S)-3-{[3-((E)-2-Piperidin-4-yl-vinyl)-[1,2,4]tria...)
Affinity DataIC50:  440nMAssay Description:Inhibition of biotinylated fibrinogen binding to immobilized integrin GPIIb/IIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed