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Found 17 Enz. Inhib. hit(s) with all data for entry = 50013272
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128419(1-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  0.600nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128428(1-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  0.800nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128423(CHEMBL299931 | {5-[1-(3,4-Bis-difluoromethoxy-phen...)
Affinity DataIC50:  0.800nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128419(1-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128417(1-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Phosphodiesterase-4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128420(1-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128419(1-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128421(1-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  2.40nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128427(4-{2-(6-benzyl-3-pyridyl)-2-[3,4-di(difluoromethox...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50064858((R)-4-(2-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-ph...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Phosphodiesterase-4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128426(2-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128425(1-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128422(CHEMBL56330 | {5-[1-(3,4-Bis-difluoromethoxy-pheny...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Phosphodiesterase-4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128416(CHEMBL57095 | {5-[1-(3,4-Bis-difluoromethoxy-pheny...)
Affinity DataIC50:  23nMAssay Description:Inhibition of Phosphodiesterase-4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128424(2-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128419(1-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  48nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50128418(1-{5-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-...)
Affinity DataIC50:  102nMAssay Description:In vitro inhibitory activity against Phosphodiesterase 4A (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed