Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50013958
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119368((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50:  9nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136366((S)-Piperidine-3-carboxylic acid [(R)-1-(4-chloro-...)
Affinity DataIC50:  9nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136357(CHEMBL341982 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Affinity DataIC50:  10nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136365(CHEMBL337571 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Affinity DataIC50:  10nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136372(CHEMBL343076 | N-{2-[(R)-1-(4-Chloro-benzyl)-2-(4-...)
Affinity DataIC50:  11nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136360(3-Acetylamino-N-[(R)-1-(4-chloro-benzyl)-2-(4-cycl...)
Affinity DataIC50:  12nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136367(CHEMBL137273 | N-{2-[(R)-1-(4-Chloro-benzyl)-2-(4-...)
Affinity DataIC50:  12nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136364((R)-Piperidine-3-carboxylic acid [(R)-1-(4-chloro-...)
Affinity DataIC50:  12nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136370(3-Benzylamino-N-[(R)-1-(4-chloro-benzyl)-2-(4-cycl...)
Affinity DataIC50:  14nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136355(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl...)
Affinity DataIC50:  16nMAssay Description:Stimulation of adenylate cyclase in HEK293 cells expressing the human MC4R receptor was determined by measuring cAMP accumulation using the RPA559 SP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136368(Azetidine-3-carboxylic acid [(R)-1-(4-chloro-benzy...)
Affinity DataIC50:  16nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136363(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl...)
Affinity DataIC50:  18nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136356(CHEMBL343742 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Affinity DataIC50:  21nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136371(CHEMBL343720 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Affinity DataIC50:  22nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136369((S)-Piperidine-3-carboxylic acid {2-[(R)-1-(4-chlo...)
Affinity DataIC50:  22nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136361((R)-Piperidine-3-carboxylic acid {2-[(R)-1-(4-chlo...)
Affinity DataIC50:  25nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136362(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl...)
Affinity DataIC50:  30nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136359(CHEMBL136366 | N-{2-[(R)-1-(4-Chloro-benzyl)-2-(4-...)
Affinity DataIC50:  90nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136373(CHEMBL340959 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Affinity DataIC50:  110nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136358(CHEMBL137318 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Affinity DataIC50:  180nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119368((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50:  3.60nMAssay Description:Stimulation of adenylate cyclase in HEK293 cells expressing the human MC4R receptor was determined by measuring cAMP accumulation using the RPA559 SP...More data for this Ligand-Target Pair
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136357(CHEMBL341982 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Affinity DataEC50:  40nMAssay Description:Stimulation of adenylate cyclase in HEK293 cells expressing the human MC4R receptor was determined by measuring cAMP accumulation using the RPA559 SP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136365(CHEMBL337571 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Affinity DataEC50:  70nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136355(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl...)
Affinity DataEC50:  170nMAssay Description:Stimulation of adenylate cyclase in HEK293 cells expressing the human MC4R receptor was determined by measuring cAMP accumulation using the RPA559 SP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed