Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50015855
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161668(1-Cyclopentylmethyl-1-(4-methanesulfonyl-phenyl)-3...)
Affinity DataEC50:  1.60E+4nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161692(1-(3-Chloro-4-methyl-phenyl)-3-(5-chloro-thiazol-2...)
Affinity DataEC50:  400nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161670(3-[3-(5-Chloro-thiazol-2-yl)-1-cyclopentylmethyl-u...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161671(3-(5-Bromo-thiazol-2-yl)-1-(4-methanesulfonyl-phen...)
Affinity DataEC50:  2.41E+4nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161672(3-(5-Bromo-thiazol-2-yl)-1-cyclopentylmethyl-1-(6-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161673(1-Cyclopentylmethyl-1-(4-methanesulfonyl-phenyl)-3...)
Affinity DataEC50:  3.42E+4nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161674(3-Cyclopentyl-2-(4-methanesulfonyl-phenyl)-N-thiaz...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effective concentration for glucokinase activation with 15 mM glucoseMore data for this Ligand-Target Pair
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161676(1-Cyclopentylmethyl-1-(3,4-difluoro-phenyl)-3-thia...)
Affinity DataEC50:  1.63E+4nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161677(4-[3-(5-Chloro-thiazol-2-yl)-1-cyclopentylmethyl-u...)
Affinity DataEC50:  1.80E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161675(3-(5-Chloro-thiazol-2-yl)-1-(4-methanesulfonyl-phe...)
Affinity DataEC50:  6.80E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161680(3-(5-Chloro-thiazol-2-yl)-1-furan-2-ylmethyl-1-(4-...)
Affinity DataEC50:  1.15E+4nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161681(3-(5-Chloro-thiazol-2-yl)-1-(6-cyano-pyridin-3-yl)...)
Affinity DataEC50:  7.70E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161682(3-(5-Chloro-thiazol-2-yl)-1-cyclopentylmethyl-1-(3...)
Affinity DataEC50:  1.40E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161678(3-(5-Chloro-thiazol-2-yl)-1-cyclopentylmethyl-1-(6...)
Affinity DataEC50:  2.70E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161679(3-(5-Chloro-thiazol-2-yl)-1-(4-cyano-phenyl)-1-cyc...)
Affinity DataEC50:  2.40E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161684(1-Cyclopentylmethyl-3-(6-methanesulfonyl-benzothia...)
Affinity DataEC50:  3.29E+4nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161685(1-Cyclopentylmethyl-1-(6-methoxy-pyridin-3-yl)-3-t...)
Affinity DataEC50:  1.92E+4nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161683(3-(5-Chloro-thiazol-2-yl)-1-(4-methanesulfonyl-phe...)
Affinity DataEC50:  4.90E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161674(3-Cyclopentyl-2-(4-methanesulfonyl-phenyl)-N-thiaz...)
Affinity DataEC50:  2.20E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161686(3-(5-Chloro-thiazol-2-yl)-1-cyclopentylmethyl-1-(4...)
Affinity DataEC50:  1.30E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161687(3-(5-Chloro-thiazol-2-yl)-1-cyclopentylmethyl-1-(4...)
Affinity DataEC50:  1.50E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161688(3-(5-Chloro-thiazol-2-yl)-1-(4-methanesulfonyl-phe...)
Affinity DataEC50:  6.60E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161689(3-(5-Chloro-thiazol-2-yl)-1-(4-methanesulfonyl-phe...)
Affinity DataEC50:  2.19E+4nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161690(3-(5-Chloro-thiazol-2-yl)-1-cyclopentylmethyl-1-(3...)
Affinity DataEC50:  2.60E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161691(CHEMBL180172 | N-{3-[3-(5-Chloro-thiazol-2-yl)-1-c...)
Affinity DataEC50:  300nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161694(3-(5-Bromo-thiazol-2-yl)-1-(4-methanesulfonyl-phen...)
Affinity DataEC50:  6.50E+3nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161693(3-(5-Chloro-thiazol-2-yl)-1-(4-methanesulfonyl-phe...)
Affinity DataEC50:  2.16E+4nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161668(1-Cyclopentylmethyl-1-(4-methanesulfonyl-phenyl)-3...)
Affinity DataEC50:  9.70E+3nMAssay Description:Effective concentration for glucokinase activation with 15 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161695(1-(4-Bromo-3-fluoro-phenyl)-3-(5-chloro-thiazol-2-...)
Affinity DataEC50:  700nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161669(1-Cyclopentylmethyl-1-(6-methoxy-pyridin-3-yl)-3-(...)
Affinity DataEC50:  2.91E+4nMAssay Description:Effective concentration for glucokinase activation with 5 mM glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed