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Found 100 Enz. Inhib. hit(s) with all data for entry = 50037654
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50366764(CHEMBL1790045 | MCL-117)
Affinity DataKi:  0.00300nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50366764(CHEMBL1790045 | MCL-117)
Affinity DataKi:  0.00300nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180190((1R,9R)-17-[(2S)-oxolan-2-ylmethyl]-17-azatetracyc...)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105483((-)-cyclorphan | 17-cyclopropylmethyl-(1R,9R)-17-a...)
Affinity DataKi:  0.0340nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  0.0490nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105483((-)-cyclorphan | 17-cyclopropylmethyl-(1R,9R)-17-a...)
Affinity DataKi:  0.0620nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180179(CHEMBL203251 | MCL-139)
Affinity DataKi:  0.0760nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135808((-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Man...)
Affinity DataKi:  0.0790nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135797(CHEMBL146756 | di[17-cyclobutylmethyl-(1R,9R,10R)-...)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180192(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-(3,6-d...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180190((1R,9R)-17-[(2S)-oxolan-2-ylmethyl]-17-azatetracyc...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180179(CHEMBL203251 | MCL-139)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135797(CHEMBL146756 | di[17-cyclobutylmethyl-(1R,9R,10R)-...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180192(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-(3,6-d...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135808((-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Man...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180183(1-((-)-N-cyclopropylmethylmorphinan-3-yl) 10-(N-cy...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180190((1R,9R)-17-[(2S)-oxolan-2-ylmethyl]-17-azatetracyc...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180185(10-{[(1R,9R)-17-(cyclobutylmethyl)-17-azatetracycl...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180187(1-phenyl 10-((-)-N-cyclobutylmethylmorphinan-3-yl)...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180183(1-((-)-N-cyclopropylmethylmorphinan-3-yl) 10-(N-cy...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180189(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-((-)-N...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180187(1-phenyl 10-((-)-N-cyclobutylmethylmorphinan-3-yl)...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50366764(CHEMBL1790045 | MCL-117)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180180(CHEMBL381750 | bis-((-)-N-cyclobutylmethylmorphina...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180189(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-((-)-N...)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180182(CHEMBL369919 | bis-((-)-N-[(S)-tetrahydrofurfuryl]...)
Affinity DataKi:  0.670nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180185(10-{[(1R,9R)-17-(cyclobutylmethyl)-17-azatetracycl...)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  0.880nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180177(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-((+)-N...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180182(CHEMBL369919 | bis-((-)-N-[(S)-tetrahydrofurfuryl]...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50138014(3-Amino-N-cyclobutylmethylmorphinan | 3-aminobutor...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50105483((-)-cyclorphan | 17-cyclopropylmethyl-(1R,9R)-17-a...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180177(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-((+)-N...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180180(CHEMBL381750 | bis-((-)-N-cyclobutylmethylmorphina...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180191(CHEMBL372598 | bis-(3-amino-(-)-N-cyclobutylmethyl...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50138014(3-Amino-N-cyclobutylmethylmorphinan | 3-aminobutor...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180191(CHEMBL372598 | bis-(3-amino-(-)-N-cyclobutylmethyl...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180192(1-((-)-N-cyclobutylmethylmorphinan-3-yl) 10-(3,6-d...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135806(CHEMBL147511 | MCL-144 | di[17-cyclobutylmethyl-(1...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180183(1-((-)-N-cyclopropylmethylmorphinan-3-yl) 10-(N-cy...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180178(CHEMBL201220 | bis-(3-amino-(-)-N-cyclobutylmethyl...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135808((-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Man...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180186(CHEMBL201219 | bis-((-)-N-cyclobutylmethylmorphina...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180178(CHEMBL201220 | bis-(3-amino-(-)-N-cyclobutylmethyl...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180182(CHEMBL369919 | bis-((-)-N-[(S)-tetrahydrofurfuryl]...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180179(CHEMBL203251 | MCL-139)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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