Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50018091
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50136234(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]iloprost from cloned human PGI2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50191133(CHEMBL439357 | sodium (R)-2-(3-((2-(4,5-diphenylox...)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]iloprost from cloned human PGI2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50191135(CHEMBL215442 | sodium 2-(3-(((1S,2R)-2-(4,5-diphen...)
Affinity DataIC50:  39nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50191133(CHEMBL439357 | sodium (R)-2-(3-((2-(4,5-diphenylox...)
Affinity DataIC50:  48nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50191134(CHEMBL379203 | sodium 2-(3-(((1S,2S)-2-(4,5-diphen...)
Affinity DataIC50:  53nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50191132(CHEMBL438092 | sodium (S)-2-(3-((2-(4,5-diphenylox...)
Affinity DataIC50:  58nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50136234(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Affinity DataIC50:  60nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50191137(CHEMBL212943 | sodium 2-(3-(((1S,2R)-2-(4,5-diphen...)
Affinity DataIC50:  114nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50191138(CHEMBL405770 | sodium 2-(3-(((1S,2S)-2-(4,5-diphen...)
Affinity DataIC50:  115nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50136237(CHEMBL132649 | Sodium; {3-[2-(4,5-diphenyl-oxazol-...)
Affinity DataIC50:  533nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(RAT)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50191133(CHEMBL439357 | sodium (R)-2-(3-((2-(4,5-diphenylox...)
Affinity DataIC50:  700nMAssay Description:Agonist activity at rat PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50191136(CHEMBL386580 | sodium 2-(3-(2-(4,5-diphenyloxazol-...)
Affinity DataIC50:  930nMAssay Description:Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(RAT)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50136234(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Agonist activity at rat PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(RAT)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50191132(CHEMBL438092 | sodium (S)-2-(3-((2-(4,5-diphenylox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at rat PGI2 receptor assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed