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Found 6 Enz. Inhib. hit(s) with all data for entry = 50021141
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50221438((1R,4R,9aS)-1-ethyl-4-hexyl-octahydro-1H-quinolizi...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of alpha4beta2 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50221439((1R,4R,9aS)-1-ethyl-4-(pent-4-enyl)-octahydro-1H-q...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of alpha4beta2 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50221438((1R,4R,9aS)-1-ethyl-4-hexyl-octahydro-1H-quinolizi...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of alpha7 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50221437((1R,4R,9aS)-1-ethyl-4-(pent-4-ynyl)-octahydro-1H-q...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of alpha4beta2 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50221439((1R,4R,9aS)-1-ethyl-4-(pent-4-enyl)-octahydro-1H-q...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of alpha7 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50221437((1R,4R,9aS)-1-ethyl-4-(pent-4-ynyl)-octahydro-1H-q...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of alpha7 nAchR expressed in Xenopus laevis oocytes assessed as acetylcholine-induced current by voltage-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed