Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 50021652
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226460(12-O-deacetyl-12-epi-19-deoxy-21-hydroxyscalarin |...)
Affinity DataIC50:  2.40E+3nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226465(CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...)
Affinity DataIC50:  4.10E+3nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226461(12-O-deacetyl-12-epi-19-O-methylscalarin | CHEMBL2...)
Affinity DataIC50:  2.40E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226463((5aS,5bR,7aS,11aS,11bR,13R,13aS,13bR)-13-hydroxy-5...)
Affinity DataIC50:  3.16E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226462(12-Episcalarin | 12-epi-scalarin | CHEMBL269105)
Affinity DataIC50:  6.04E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226459(12-O-deacetyl-12-epi-scalarin | CHEMBL399743)
Affinity DataIC50:  7.50E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226464(12-O-deacetyl-12-epi-19-deoxy-22-hydroxyscalarin |...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed