Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 3086
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27826(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 9 | 4...)
Affinity DataIC50:  0.300nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27825(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 8 | 4...)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27842(4,5-difluoro-2-{[2-({2-methoxy-4-[4-(propan-2-yl)p...)
Affinity DataIC50:  0.5nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27822(2-[(2-{[2-methoxy-4-(1-propyl-1,2,5,6-tetrahydropy...)
Affinity DataIC50:  0.600nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27823(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 6 | 4...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27841(2,4-difluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)p...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27839(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 25 | ...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27828(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 11 | ...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27838(2-{[2-({2-methoxy-4-[4-(propan-2-yl)piperazin-1-yl...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27840(2,3-difluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)p...)
Affinity DataIC50:  1.30nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27819(2-[(2-{[4-(1-propyl-1,2,5,6-tetrahydropyridin-3-yl...)
Affinity DataIC50:  1.60nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27827(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 10 | ...)
Affinity DataIC50:  1.60nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27829(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 12 | ...)
Affinity DataIC50:  1.60nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27835(2-{[2-({5-chloro-2-methoxy-4-[4-(propan-2-yl)piper...)
Affinity DataIC50:  1.60nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27820(2-[(2-{[2-fluoro-4-(1-propyl-1,2,5,6-tetrahydropyr...)
Affinity DataIC50:  1.60nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27783(2-fluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)piper...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27833(2-fluoro-6-{[2-({5-fluoro-2-methoxy-4-[4-(propan-2...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27834(2-fluoro-6-{[2-({2-methoxy-5-methyl-4-[4-(propan-2...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27832(2-{[2-({2,5-dimethoxy-4-[4-(propan-2-yl)piperazin-...)
Affinity DataIC50:  3.20nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27844(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 30 | ...)
Affinity DataIC50:  3.20nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27824(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 7 | 4...)
Affinity DataIC50:  3.20nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27784(2-fluoro-6-{[2-({2-methoxy-5-[4-(propan-2-yl)piper...)
Affinity DataIC50:  4nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27836(2-fluoro-6-{[2-({3-fluoro-2-methoxy-4-[4-(propan-2...)
Affinity DataIC50:  4nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27843(2-fluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)piper...)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27847(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 33 | ...)
Affinity DataIC50:  5nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27818(2-[(2-{[2-methyl-4-(1-propyl-1,2,5,6-tetrahydropyr...)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27845(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 31 | ...)
Affinity DataIC50:  6.30nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27837(2-fluoro-6-{[2-({2-methoxy-3-methyl-4-[4-(propan-2...)
Affinity DataIC50:  8nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27846(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 32 | ...)
Affinity DataIC50:  16nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27821(2-[(2-{[4-(1-propyl-1,2,5,6-tetrahydropyridin-3-yl...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27785(2-fluoro-6-{[2-({2-methoxy-4-methyl-5-[4-(propan-2...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27848(4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine, 34 | ...)
Affinity DataIC50:  25nMAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27830(2-fluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)piper...)
Affinity DataIC50:  50nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM27831(2-fluoro-6-{[2-({2-methoxy-4-[4-(propan-2-yl)piper...)
Affinity DataIC50:  1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed