Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50030273
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293525(5-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293515(2-(4-methylthiazol-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293527(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinolin-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293526(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)thieno[3,...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293516(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293520(CHEMBL537968 | N-(1H-indazol-5-yl)-2-(6-methylpyri...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293519(2-(6-methylpyridin-2-yl)-N-(pyrimidin-4-yl)quinazo...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293514(2-(3-chlorophenyl)-N-(pyridin-4-yl)quinazolin-4-am...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293527(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinolin-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293519(2-(6-methylpyridin-2-yl)-N-(pyrimidin-4-yl)quinazo...)
Affinity DataIC50:  60nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293526(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)thieno[3,...)
Affinity DataIC50:  60nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293520(CHEMBL537968 | N-(1H-indazol-5-yl)-2-(6-methylpyri...)
Affinity DataIC50:  90nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293524(6-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)...)
Affinity DataIC50:  93nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293516(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50:  95nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293513(2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine | CHEM...)
Affinity DataIC50:  194nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293517(2-(6-methylpyridin-2-yl)-N-(2-methylpyridin-4-yl)q...)
Affinity DataIC50:  199nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293518(3-(2-(6-methylpyridin-2-yl)quinazolin-4-ylamino)be...)
Affinity DataIC50:  263nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293525(5-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)...)
Affinity DataIC50:  318nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293515(2-(4-methylthiazol-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50:  342nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293518(3-(2-(6-methylpyridin-2-yl)quinazolin-4-ylamino)be...)
Affinity DataIC50:  545nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293521(CHEMBL550482 | N-(1-methyl-1H-indazol-5-yl)-2-(6-m...)
Affinity DataIC50:  588nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293522(CHEMBL550483 | N-(2-(6-methylpyridin-2-yl)quinazol...)
Affinity DataIC50:  646nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293524(6-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)...)
Affinity DataIC50:  745nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293521(CHEMBL550482 | N-(1-methyl-1H-indazol-5-yl)-2-(6-m...)
Affinity DataIC50:  794nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293517(2-(6-methylpyridin-2-yl)-N-(2-methylpyridin-4-yl)q...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293513(2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine | CHEM...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293514(2-(3-chlorophenyl)-N-(pyridin-4-yl)quinazolin-4-am...)
Affinity DataIC50:  1.61E+3nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293513(2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine | CHEM...)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293523(CHEMBL563207 | N-(1H-benzo[d][1,2,3]triazol-6-yl)-...)
Affinity DataIC50:  3.72E+3nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293523(CHEMBL563207 | N-(1H-benzo[d][1,2,3]triazol-6-yl)-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293522(CHEMBL550483 | N-(2-(6-methylpyridin-2-yl)quinazol...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293516(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50:  6.72E+3nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293517(2-(6-methylpyridin-2-yl)-N-(2-methylpyridin-4-yl)q...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293519(2-(6-methylpyridin-2-yl)-N-(pyrimidin-4-yl)quinazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293518(3-(2-(6-methylpyridin-2-yl)quinazolin-4-ylamino)be...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293523(CHEMBL563207 | N-(1H-benzo[d][1,2,3]triazol-6-yl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293522(CHEMBL550483 | N-(2-(6-methylpyridin-2-yl)quinazol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293521(CHEMBL550482 | N-(1-methyl-1H-indazol-5-yl)-2-(6-m...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293520(CHEMBL537968 | N-(1H-indazol-5-yl)-2-(6-methylpyri...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293515(2-(4-methylthiazol-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293514(2-(3-chlorophenyl)-N-(pyridin-4-yl)quinazolin-4-am...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed