Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50030593
TargetP2X purinoceptor 7(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50298708(CHEMBL574539 | [3H]A-804598)
Affinity DataIC50:  10nMAssay Description:Binding affinity at human P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Mus musculus)
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50298708(CHEMBL574539 | [3H]A-804598)
Affinity DataIC50:  10nMAssay Description:Binding affinity at mouse P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50298708(CHEMBL574539 | [3H]A-804598)
Affinity DataIC50:  10nMAssay Description:Binding affinity at rat P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50234965(A-740003 | CHEMBL255787 | N-(1-(2-cyano-3-(quinoli...)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of agonist-induced calcium flux by fluoro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50234965(A-740003 | CHEMBL255787 | N-(1-(2-cyano-3-(quinoli...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of agonist-induced calcium flux by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50234965(A-740003 | CHEMBL255787 | N-(1-(2-cyano-3-(quinoli...)
Affinity DataIC50:  92nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced pore formation flux by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50234965(A-740003 | CHEMBL255787 | N-(1-(2-cyano-3-(quinoli...)
Affinity DataIC50:  156nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human THP1 cells assessed as inhibition of BzATP-induced IL1beta release by enzym...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced pore formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50298709(CHEMBL585553 | Stylissadine A)
Affinity DataIC50:  700nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced pore formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50298710(CHEMBL582937 | Stylissadine B)
Affinity DataIC50:  1.80E+3nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced pore formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed