Compile Data Set for Download or QSAR
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Found 31 Enz. Inhib. hit(s) with all data for entry = 50031345
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311624(3,4-difluoro-N-(5-(5-fluoro-3-methyl-1-(naphthalen...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311623(CHEMBL1081186 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311621(3,4-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311615(4,5-dichloro-N-(5-(5-fluoro-3-methyl-1-(naphthalen...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311610(4,5-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311619(CHEMBL1080106 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311618(CHEMBL1080105 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311622(3,4-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303662(3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-ind...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311614(4,5-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311617(2,4,5-trifluoro-N-(5-(5-fluoro-3-methyl-1-(naphtha...)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311611(4,5-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311620(3,4-dichloro-N-(5-(5-fluoro-3-methyl-1-(naphthalen...)
Affinity DataIC50:  11nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311626(CHEMBL1079409 | N-(5-(1-(3,4-difluorobenzyl)-5-flu...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311625(CHEMBL1080281 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311612(4,5-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50:  24nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311627(CHEMBL1079767 | N-(5-(1-(3,4-difluorobenzyl)-5-flu...)
Affinity DataIC50:  44nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311613(4,5-dichloro-N-(5-(1-(3,4-difluorobenzyl)-5-fluoro...)
Affinity DataIC50:  59nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311632(CHEMBL1086634 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  244nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311631(CHEMBL1086633 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  363nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311623(CHEMBL1081186 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  600nMAssay Description:Binding affinity to human FP receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311628(CHEMBL1079936 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  664nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311630(CHEMBL1087149 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  1.02E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311629(2,4-dichloro-N-(5-(1-(2,4-dichlorobenzyl)-5-fluoro...)
Affinity DataIC50:  1.32E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311616(4,5-dichloro-N-(5-(1-(3,4-difluorobenzyl)-5-fluoro...)
Affinity DataIC50:  1.98E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311633(CHEMBL1086762 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  2.57E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311634(CHEMBL1088322 | N-(3-(1-(2,4-difluorobenzyl)-5-flu...)
Affinity DataIC50:  1.79E+4nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311623(CHEMBL1081186 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  1.86E+4nMAssay Description:Binding affinity to human EP4 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311623(CHEMBL1081186 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50:  1.98E+4nMAssay Description:Binding affinity to human EP2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311623(CHEMBL1081186 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50: >2.00E+4nMAssay Description:Binding affinity to human IP receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50311623(CHEMBL1081186 | N-(5-(1-(2,4-dichlorobenzyl)-5-flu...)
Affinity DataIC50: >2.00E+4nMAssay Description:Binding affinity to human EP1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed