Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50030870
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303103(1-(3-(3-(4-chloro-3-hydroxyphenyl)-2-(pyridin-4-yl...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303121(CHEMBL585144 | ethyl 3-(3-(7-chloro-1H-indazol-4-y...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303123(CHEMBL570681 | ethyl 3-(3-(7-fluoro-1H-indazol-4-y...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303098(5-(7-(8-azabicyclo[3.2.1]octan-3-yl)-2-(pyridin-4-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303100(2-chloro-5-(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303131(2-chloro-5-[13-(hydroxymethyl)-15-methyl-5-(pyridi...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303127(CHEMBL583133 | ethyl 3-(3-(7-methyl-1H-indazol-4-y...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303132(2-chloro-5-[13-(hydroxymethyl)-15-methyl-5-(pyridi...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303094(CHEMBL571129 | ethyl 3-(3-(3-hydroxyphenyl)-2-(pyr...)
Affinity DataIC50:  1nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303130(CHEMBL585148 | Methyl 6-(4-chloro-3-hydroxyphenyl)...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303110(CHEMBL585334 | ethyl 3-(3-(1H-indazol-4-yl)-2-(pyr...)
Affinity DataIC50:  2nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303111((2R)-1-(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyr...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303102(5-(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-2-(py...)
Affinity DataIC50:  3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303124(7-(8-azabicyclo[3.2.1]octan-3-yl)-3-(7-fluoro-1H-i...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303097(3-(7-(8-azabicyclo[3.2.1]octan-3-yl)-2-(pyridin-4-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303122(3-(7-chloro-1H-indazol-4-yl)-7-(8-ethyl-8-azabicyc...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303125(CHEMBL571744 | ethyl 3-(2-(pyridin-4-yl)-3-(7-(tri...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303112(3-(1H-indazol-4-yl)-7-(8-(methylsulfonyl)-8-azabic...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303113(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dihydr...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303114(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dihydr...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303129(CHEMBL585335 | ethyl 3-(3-(1H-indazol-4-yl)-6-meth...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303096(7-(8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chloro-3-me...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303115(1-(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dih...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303128(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-3-(7-met...)
Affinity DataIC50:  17nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303116(2-(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dih...)
Affinity DataIC50:  22.8nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303106(CHEMBL583894 | ethyl 3-(3-(1H-indol-6-yl)-2-(pyrid...)
Affinity DataIC50:  36nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303117((2R)-tert-butyl 1-(3-(3-(1H-indazol-4-yl)-2-(pyrid...)
Affinity DataIC50:  39.4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303099(3-(4-chloro-3-methoxyphenyl)-7-(8-ethyl-8-azabicyc...)
Affinity DataIC50:  43.5nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303126(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-2-(pyrid...)
Affinity DataIC50:  45nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303118(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-3-(1H-in...)
Affinity DataIC50:  46.6nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303093(CHEMBL584739 | ethyl 3-(3-(4-chloro-3-methoxypheny...)
Affinity DataIC50:  54.1nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303101(4-(7-(8-ethyl-8-azabicyclo[3.2.1]octan-3-yl)-2-(py...)
Affinity DataIC50:  57.9nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303119(3-(1H-indazol-4-yl)-7-(8-isopropyl-8-azabicyclo[3....)
Affinity DataIC50:  67nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303095(7-(8-azabicyclo[3.2.1]octan-3-yl)-3-(3-methoxyphen...)
Affinity DataIC50:  70.8nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303120(1-(3-(3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-1,2-dih...)
Affinity DataIC50:  75.9nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303092(CHEMBL571557 | ethyl 3-(3-(3-methoxyphenyl)-2-(pyr...)
Affinity DataIC50:  87nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303105(CHEMBL583340 | ethyl 3-(3-(4-(1,3,4-oxadiazol-2-yl...)
Affinity DataIC50:  151nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303104(CHEMBL571558 | ethyl 3-(3-(3,4-difluorophenyl)-2-(...)
Affinity DataIC50:  302nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303109(CHEMBL569534 | ethyl 3-(3-(2-oxo-2,3-dihydro-1H-be...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303107(CHEMBL570416 | ethyl 3-(3-(1H-indol-4-yl)-2-(pyrid...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303108(CHEMBL568856 | ethyl 3-(3-(2-oxoindolin-6-yl)-2-(p...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed